Determination of intracellular electrical parameters in bioelectrical impedance analysis

Creating a frequency characteristic curve for bioelectrical impedance analysis involves analyzing electrical resistance (impedance) values at different frequencies. This curve is used to evaluate the electrical properties of biological tissues or fluids. In the article, the impedance of the intracel...

Full description

Bibliographic Details
Main Authors: Gafarov Gadir, Takhumova Oksana, Nikolaev Petr
Format: Article
Language:English
Published: EDP Sciences 2023-01-01
Series:BIO Web of Conferences
Online Access:https://www.bio-conferences.org/articles/bioconf/pdf/2023/16/bioconf_cibta2023_01114.pdf
_version_ 1797364696053972992
author Gafarov Gadir
Takhumova Oksana
Nikolaev Petr
author_facet Gafarov Gadir
Takhumova Oksana
Nikolaev Petr
author_sort Gafarov Gadir
collection DOAJ
description Creating a frequency characteristic curve for bioelectrical impedance analysis involves analyzing electrical resistance (impedance) values at different frequencies. This curve is used to evaluate the electrical properties of biological tissues or fluids. In the article, the impedance of the intracellular environment was evaluated and frequency dependence was established based on the electrical circuit model of the biological system. Xc = f(f), Z = f(f), φ= f(f) tgδ= f(f), dependencies were created for different frequency values of the intracellular environment in the Matlab program through a series-connected RC circuit. Regression and general statistical analyzes were performed. The most appropriate frequency range was determined to evaluate the impedance of the intracellular environment. The correlation relationship of electrical and dielectric parameters of the intracellular environment was also taken into account. Purpose: The main goal of the research is the selection of the optimal frequency range for bioimpedance analysis. In particular, the selection of the most optimal frequency was carried out in the assessment of intracellular electrical activity. The frequency range is determined depending on the electrical and dielectric parameters of the cell. Materials and Methods: Using the Matlab program, the equivalent circuit model of the cell was assembled. Frequency dependence of electrical and dielectric parameters characterizing intracellular processes was performed by model-based measurements. Conclusion: According to the obtained value, regression and general statistical analyzes were performed for the dependencies Xc=f(f), Z=f(f), φ=f(f), tgδ=f(f). Based on analysis of variance (Analysis of Variance-ANOVA) of the output variables, statistical parameters were determined for each dependency.
first_indexed 2024-03-08T16:38:53Z
format Article
id doaj.art-206f33e6ddf5429bacdb2ad08e4435f1
institution Directory Open Access Journal
issn 2117-4458
language English
last_indexed 2024-03-08T16:38:53Z
publishDate 2023-01-01
publisher EDP Sciences
record_format Article
series BIO Web of Conferences
spelling doaj.art-206f33e6ddf5429bacdb2ad08e4435f12024-01-05T10:34:06ZengEDP SciencesBIO Web of Conferences2117-44582023-01-01710111410.1051/bioconf/20237101114bioconf_cibta2023_01114Determination of intracellular electrical parameters in bioelectrical impedance analysisGafarov Gadir0Takhumova Oksana1Nikolaev Petr2Azerbaijan State Oil and Industry UniversityKuban State Agrarian University named after I.T. TrubilinSamara State University of EconomicsCreating a frequency characteristic curve for bioelectrical impedance analysis involves analyzing electrical resistance (impedance) values at different frequencies. This curve is used to evaluate the electrical properties of biological tissues or fluids. In the article, the impedance of the intracellular environment was evaluated and frequency dependence was established based on the electrical circuit model of the biological system. Xc = f(f), Z = f(f), φ= f(f) tgδ= f(f), dependencies were created for different frequency values of the intracellular environment in the Matlab program through a series-connected RC circuit. Regression and general statistical analyzes were performed. The most appropriate frequency range was determined to evaluate the impedance of the intracellular environment. The correlation relationship of electrical and dielectric parameters of the intracellular environment was also taken into account. Purpose: The main goal of the research is the selection of the optimal frequency range for bioimpedance analysis. In particular, the selection of the most optimal frequency was carried out in the assessment of intracellular electrical activity. The frequency range is determined depending on the electrical and dielectric parameters of the cell. Materials and Methods: Using the Matlab program, the equivalent circuit model of the cell was assembled. Frequency dependence of electrical and dielectric parameters characterizing intracellular processes was performed by model-based measurements. Conclusion: According to the obtained value, regression and general statistical analyzes were performed for the dependencies Xc=f(f), Z=f(f), φ=f(f), tgδ=f(f). Based on analysis of variance (Analysis of Variance-ANOVA) of the output variables, statistical parameters were determined for each dependency.https://www.bio-conferences.org/articles/bioconf/pdf/2023/16/bioconf_cibta2023_01114.pdf
spellingShingle Gafarov Gadir
Takhumova Oksana
Nikolaev Petr
Determination of intracellular electrical parameters in bioelectrical impedance analysis
BIO Web of Conferences
title Determination of intracellular electrical parameters in bioelectrical impedance analysis
title_full Determination of intracellular electrical parameters in bioelectrical impedance analysis
title_fullStr Determination of intracellular electrical parameters in bioelectrical impedance analysis
title_full_unstemmed Determination of intracellular electrical parameters in bioelectrical impedance analysis
title_short Determination of intracellular electrical parameters in bioelectrical impedance analysis
title_sort determination of intracellular electrical parameters in bioelectrical impedance analysis
url https://www.bio-conferences.org/articles/bioconf/pdf/2023/16/bioconf_cibta2023_01114.pdf
work_keys_str_mv AT gafarovgadir determinationofintracellularelectricalparametersinbioelectricalimpedanceanalysis
AT takhumovaoksana determinationofintracellularelectricalparametersinbioelectricalimpedanceanalysis
AT nikolaevpetr determinationofintracellularelectricalparametersinbioelectricalimpedanceanalysis