Pharmacokinetic/pharmacodynamic modelling to evaluate the efficacy of various dosing regimens of ceftazidime/avibactam in patients with pneumonia caused by Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae: a multicentre study in northern China

Pharmacokinetic/pharmacodynamic modelling to evaluate the efficacy of various dosing regimens of ceftazidime/avibactam in patients with pneumonia caused by Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae: a multicentre study in northern China

ABSTRACT: Objectives: The objective of this study was to evaluate the efficacy of different dosing regimens of ceftazidime/avibactam (CZA) in patients with Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-Kp) pulmonary infections. Methods: A total of 70 KPC-Kp strains were isolated...

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Bibliographic Details
Main Authors:	Yixin Kang, Qian Zhou, Junchang Cui
Format:	Article
Language:	English
Published:	Elsevier 2021-12-01
Series:	Journal of Global Antimicrobial Resistance
Subjects:	Ceftazidime/avibactam Pharmacokinetic/pharmacodynamic Monte Carlo simulation Klebsiella pneumoniae carbapenemase KPC KPC-producing K. pneumoniae
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213716521001909

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