Antimicrobial Resistance, an Update from the Ward: Increased Incidence of New Potential Pathogens and Site of Infection-Specific Antibacterial Resistances
In order to monitor the spread of antimicrobial resistance, the European Union requires hospitals to be equipped with infection control centers. With this aim, we analyzed 1583 bacterial strains isolated from samples of different origin from patients with community-onset and nosocomial infections in...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-09-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/9/9/631 |
| _version_ | 1797553016329469952 |
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| author | Irene Stefanini Martina Boni Paola Silvaplana Paola Lovera Stefania Pelassa Giuseppe De Renzi Barbara Mognetti |
| author_facet | Irene Stefanini Martina Boni Paola Silvaplana Paola Lovera Stefania Pelassa Giuseppe De Renzi Barbara Mognetti |
| author_sort | Irene Stefanini |
| collection | DOAJ |
| description | In order to monitor the spread of antimicrobial resistance, the European Union requires hospitals to be equipped with infection control centers. With this aim, we analyzed 1583 bacterial strains isolated from samples of different origin from patients with community-onset and nosocomial infections in a public tertiary University Hospital on the outskirts of Turin, Italy. Statistical analyses of the isolates (source, type) and their antimicrobial resistance (AMR) were performed. The survey revealed infections associated with bacterial species considered as not-commensal and not-pathogenic, hence potentially emerging as new threats for human health. Conversely to the general observation of nosocomial strains being more resistant to antibiotics compared to community-acquired strains, nosocomial strains isolated in this study were more resistant only to 1/42 tested antibiotics (tetracycline). By adopting an ecological approach, we observed that blood infections are associated with the broadest range of species compared to infections affecting other areas and we obtained clear indications on the antibiotics that should be preferred in the treatment of infections at specific body sites. Future investigations carried out on a larger geographical scale will clarify whether these indications are limited to the geographical region investigated over this study, or whether the same trends are visible at national or international level. |
| first_indexed | 2024-03-10T16:09:24Z |
| format | Article |
| id | doaj.art-2070bbad87ed4467aa941ac58bd4ec4d |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-10T16:09:24Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-2070bbad87ed4467aa941ac58bd4ec4d2023-11-20T14:35:57ZengMDPI AGAntibiotics2079-63822020-09-019963110.3390/antibiotics9090631Antimicrobial Resistance, an Update from the Ward: Increased Incidence of New Potential Pathogens and Site of Infection-Specific Antibacterial ResistancesIrene Stefanini0Martina Boni1Paola Silvaplana2Paola Lovera3Stefania Pelassa4Giuseppe De Renzi5Barbara Mognetti6Department of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Turin, ItalyDepartment of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Turin, ItalyInfectious Risk Prevention Unit, San Luigi Gonzaga University Hospital, Regione Gonzole 10, Orbassano, 10043 Turin, ItalyInfectious Risk Prevention Unit, San Luigi Gonzaga University Hospital, Regione Gonzole 10, Orbassano, 10043 Turin, ItalyInfectious Risk Prevention Unit, San Luigi Gonzaga University Hospital, Regione Gonzole 10, Orbassano, 10043 Turin, ItalySCDO Laboratory of Clinical Pathology and Microbiology, San Luigi Gonzaga University Hospital, Regione Gonzole 10, Orbassano, 10043 Turin, ItalyDepartment of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Turin, ItalyIn order to monitor the spread of antimicrobial resistance, the European Union requires hospitals to be equipped with infection control centers. With this aim, we analyzed 1583 bacterial strains isolated from samples of different origin from patients with community-onset and nosocomial infections in a public tertiary University Hospital on the outskirts of Turin, Italy. Statistical analyses of the isolates (source, type) and their antimicrobial resistance (AMR) were performed. The survey revealed infections associated with bacterial species considered as not-commensal and not-pathogenic, hence potentially emerging as new threats for human health. Conversely to the general observation of nosocomial strains being more resistant to antibiotics compared to community-acquired strains, nosocomial strains isolated in this study were more resistant only to 1/42 tested antibiotics (tetracycline). By adopting an ecological approach, we observed that blood infections are associated with the broadest range of species compared to infections affecting other areas and we obtained clear indications on the antibiotics that should be preferred in the treatment of infections at specific body sites. Future investigations carried out on a larger geographical scale will clarify whether these indications are limited to the geographical region investigated over this study, or whether the same trends are visible at national or international level.https://www.mdpi.com/2079-6382/9/9/631bacterial infectionantimicrobial resistancenosocomial infectionscommunity-acquired infections |
| spellingShingle | Irene Stefanini Martina Boni Paola Silvaplana Paola Lovera Stefania Pelassa Giuseppe De Renzi Barbara Mognetti Antimicrobial Resistance, an Update from the Ward: Increased Incidence of New Potential Pathogens and Site of Infection-Specific Antibacterial Resistances Antibiotics bacterial infection antimicrobial resistance nosocomial infections community-acquired infections |
| title | Antimicrobial Resistance, an Update from the Ward: Increased Incidence of New Potential Pathogens and Site of Infection-Specific Antibacterial Resistances |
| title_full | Antimicrobial Resistance, an Update from the Ward: Increased Incidence of New Potential Pathogens and Site of Infection-Specific Antibacterial Resistances |
| title_fullStr | Antimicrobial Resistance, an Update from the Ward: Increased Incidence of New Potential Pathogens and Site of Infection-Specific Antibacterial Resistances |
| title_full_unstemmed | Antimicrobial Resistance, an Update from the Ward: Increased Incidence of New Potential Pathogens and Site of Infection-Specific Antibacterial Resistances |
| title_short | Antimicrobial Resistance, an Update from the Ward: Increased Incidence of New Potential Pathogens and Site of Infection-Specific Antibacterial Resistances |
| title_sort | antimicrobial resistance an update from the ward increased incidence of new potential pathogens and site of infection specific antibacterial resistances |
| topic | bacterial infection antimicrobial resistance nosocomial infections community-acquired infections |
| url | https://www.mdpi.com/2079-6382/9/9/631 |
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