Development of technology for obtaining a liquid extract of medicinal sage ( Salvia officinalis L.)

Inflammatory diseases of the female genital area are dominant among the total number of gynecological diseases. Among all the variety of medicinal plant materials used in official medicine, salvia medicinal draws attention to itself, which has repeatedly proved its effectiveness in the treatment of...

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Main Authors: Moldavanova Anastasia, Malyutina Anastasia, Kozubova Larissa, Kazakova Valentina, Shestopalova Natalia
Format: Article
Language:English
Published: EDP Sciences 2021-01-01
Series:BIO Web of Conferences
Subjects:
Online Access:https://www.bio-conferences.org/articles/bioconf/pdf/2021/12/bioconf_ils21_03004.pdf
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author Moldavanova Anastasia
Malyutina Anastasia
Kozubova Larissa
Kazakova Valentina
Shestopalova Natalia
author_facet Moldavanova Anastasia
Malyutina Anastasia
Kozubova Larissa
Kazakova Valentina
Shestopalova Natalia
author_sort Moldavanova Anastasia
collection DOAJ
description Inflammatory diseases of the female genital area are dominant among the total number of gynecological diseases. Among all the variety of medicinal plant materials used in official medicine, salvia medicinal draws attention to itself, which has repeatedly proved its effectiveness in the treatment of inflammatory diseases of the mucous membranes of various origins. That is why the goal was set to develop a technology for obtaining a liquid extract from the leaves of Salvia officinalis L. As a result of the study, a method was developed for obtaining a liquid extract by selecting the optimal extraction conditions. It was found that the optimal raw material-extractant ratio is 1:50, the optimal concentration of the extractant ethyl alcohol is 70%, the infusion time of the extract is 24 hours. To intensify the extraction process, the method of ultrasonic processing of raw materials at the soaking stage was used. The optimal time for processing plant materials with ultrasound was 45 minutes. As a result of using this method to obtain a liquid extract from the leaves of sage officinalis, the yield of phenolic compounds was doubled in comparison with obtaining an extract without sonication of raw materials and amounted to 182.7 mg / g of flavonoids in terms of luteolin-7-glycoside.
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spelling doaj.art-207205af014947feb88d7793ee0526a32022-12-21T17:24:31ZengEDP SciencesBIO Web of Conferences2117-44582021-01-01400300410.1051/bioconf/20214003004bioconf_ils21_03004Development of technology for obtaining a liquid extract of medicinal sage ( Salvia officinalis L.)Moldavanova Anastasia0Malyutina Anastasia1Kozubova Larissa2Kazakova Valentina3Shestopalova Natalia4Belgorod State National Research UniversityBelgorod State National Research UniversityBelgorod State National Research UniversityBelgorod State National Research UniversityBelgorod State National Research UniversityInflammatory diseases of the female genital area are dominant among the total number of gynecological diseases. Among all the variety of medicinal plant materials used in official medicine, salvia medicinal draws attention to itself, which has repeatedly proved its effectiveness in the treatment of inflammatory diseases of the mucous membranes of various origins. That is why the goal was set to develop a technology for obtaining a liquid extract from the leaves of Salvia officinalis L. As a result of the study, a method was developed for obtaining a liquid extract by selecting the optimal extraction conditions. It was found that the optimal raw material-extractant ratio is 1:50, the optimal concentration of the extractant ethyl alcohol is 70%, the infusion time of the extract is 24 hours. To intensify the extraction process, the method of ultrasonic processing of raw materials at the soaking stage was used. The optimal time for processing plant materials with ultrasound was 45 minutes. As a result of using this method to obtain a liquid extract from the leaves of sage officinalis, the yield of phenolic compounds was doubled in comparison with obtaining an extract without sonication of raw materials and amounted to 182.7 mg / g of flavonoids in terms of luteolin-7-glycoside.https://www.bio-conferences.org/articles/bioconf/pdf/2021/12/bioconf_ils21_03004.pdfsalvia officinalis ltechnologyliquid extractmedical sage
spellingShingle Moldavanova Anastasia
Malyutina Anastasia
Kozubova Larissa
Kazakova Valentina
Shestopalova Natalia
Development of technology for obtaining a liquid extract of medicinal sage ( Salvia officinalis L.)
BIO Web of Conferences
salvia officinalis l
technology
liquid extract
medical sage
title Development of technology for obtaining a liquid extract of medicinal sage ( Salvia officinalis L.)
title_full Development of technology for obtaining a liquid extract of medicinal sage ( Salvia officinalis L.)
title_fullStr Development of technology for obtaining a liquid extract of medicinal sage ( Salvia officinalis L.)
title_full_unstemmed Development of technology for obtaining a liquid extract of medicinal sage ( Salvia officinalis L.)
title_short Development of technology for obtaining a liquid extract of medicinal sage ( Salvia officinalis L.)
title_sort development of technology for obtaining a liquid extract of medicinal sage salvia officinalis l
topic salvia officinalis l
technology
liquid extract
medical sage
url https://www.bio-conferences.org/articles/bioconf/pdf/2021/12/bioconf_ils21_03004.pdf
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AT kozubovalarissa developmentoftechnologyforobtainingaliquidextractofmedicinalsagesalviaofficinalisl
AT kazakovavalentina developmentoftechnologyforobtainingaliquidextractofmedicinalsagesalviaofficinalisl
AT shestopalovanatalia developmentoftechnologyforobtainingaliquidextractofmedicinalsagesalviaofficinalisl