Chimeric Peptides from <i>Californiconus californicus</i> and <i>Heterodontus francisci</i> with Antigen-Binding Capacity: A Conotoxin Scaffold to Create Non-Natural Antibodies (NoNaBodies)

Chimeric Peptides from <i>Californiconus californicus</i> and <i>Heterodontus francisci</i> with Antigen-Binding Capacity: A Conotoxin Scaffold to Create Non-Natural Antibodies (NoNaBodies)

Research into various proteins capable of blocking metabolic pathways has improved the detection and treatment of multiple pathologies associated with the malfunction and overexpression of different metabolites. However, antigen-binding proteins have limitations. To overcome the disadvantages of the...

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Bibliographic Details
Main Authors: Salvador Dueñas, Teresa Escalante, Jahaziel Gasperin-Bulbarela, Johanna Bernáldez-Sarabia, Karla Cervantes-Luévano, Samanta Jiménez, Noemí Sánchez-Campos, Olivia Cabanillas-Bernal, Blanca J. Valdovinos-Navarro, Angélica Álvarez-Lee, Marco A. De León-Nava, Alexei F. Licea-Navarro
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Toxins
Subjects:
NoNaBody
miniprotein design
VNAR and conotoxin fusion
chimeric peptide
protein scaffold
Online Access:https://www.mdpi.com/2072-6651/15/4/269

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