REV1: A novel biomarker and potential therapeutic target for various cancers

Background: REV1 is a member of the translesion synthesis DNA polymerase Y family. It is an essential player in a variety of DNA replication activities, and perform major roles in the production of both spontaneous and DNA damage-induced mutations. This study aimed to explore the role of REV1 as a p...

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Bibliographic Details
Main Authors: Ning Zhu, Yingxin Zhao, Mi Mi, Yier Lu, Yinuo Tan, Xuefeng Fang, Shanshan Weng, Ying Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.997970/full