Variation of serum serotonin values under specific peloidotherapy in patients with degenerative pathology of the lumbar spine
Serotonin is well known to be involved in the mediation of cognitive processes, but also in the regulation of multiple distinct physiological processes, such as pain. It is also involved in the modulation of nociception of the endogenous analgesic system. Among the monoamine neurotransmitters, serot...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Romanian Association of Balneology, Editura Balneara
2023-09-01
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| Series: | Balneo and PRM Research Journal |
| Subjects: | |
| Online Access: | http://bioclima.ro/Balneo588.pdf |
| _version_ | 1797666892300681216 |
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| author | Andreea-Alexandra Lupu Doinita Oprea Bogdan Obada Dan Marcel Iliescu Mihaela Botnarciuc Ana-Maria Ionescu Claudia Ileana Mihailov Madalina-Gabriela Iliescu Bogdan Marian Caraban |
| author_facet | Andreea-Alexandra Lupu Doinita Oprea Bogdan Obada Dan Marcel Iliescu Mihaela Botnarciuc Ana-Maria Ionescu Claudia Ileana Mihailov Madalina-Gabriela Iliescu Bogdan Marian Caraban |
| author_sort | Andreea-Alexandra Lupu |
| collection | DOAJ |
| description | Serotonin is well known to be involved in the mediation of cognitive processes, but also in the regulation of multiple distinct physiological processes, such as pain. It is also involved in the modulation of nociception of the endogenous analgesic system. Among the monoamine neurotransmitters, serotonin plays an important role in signaling chronic pain, hence the importance of its monitoring in lumbar pain due to degenerative pathology, one of the common cause of this kind of pain. The aim of our study is to evaluate the impact of peloidotherapy on the variation of serum serotonin levels in patients with degenerative low back pain. In our study, conducted in Balneal and Rehabilitation Sanatorium of Techirghiol, we evaluated 130 patients who performed balneal and physical treatments for a period of 2 weeks. The patients were divided into 3 groups: 51 patients were enrolled into the hot mud baths group (HMB), 48 in the cold mud baths (CMB) group and 31 in the control group (CG). Each patient performed physiotherapy treatments which includes electrotherapy, massage and kinetotherapy, patients from HMB group had also hot mud therapy and patients from CMB group had cold mud therapy. Serum serotonin was dosed at admission and at discharge, for each patient, and was determined using ELISA method with kits from Demeditec Diagnostics GmbH for human serotonin. All the data from the study were statistically analized using the SPSS 22.0 program, values were interpreted as mean value and standard deviation, and we used ANOVA and t tests. The statistically significant value considered was p<0.05. |
| first_indexed | 2024-03-11T20:05:07Z |
| format | Article |
| id | doaj.art-2081d17ad8d24a1594fab63ff7cac838 |
| institution | Directory Open Access Journal |
| issn | 2734-8458 |
| language | English |
| last_indexed | 2024-03-11T20:05:07Z |
| publishDate | 2023-09-01 |
| publisher | Romanian Association of Balneology, Editura Balneara |
| record_format | Article |
| series | Balneo and PRM Research Journal |
| spelling | doaj.art-2081d17ad8d24a1594fab63ff7cac8382023-10-03T20:19:34ZengRomanian Association of Balneology, Editura BalnearaBalneo and PRM Research Journal2734-84582023-09-0114358810.12680/balneo.2023.588Variation of serum serotonin values under specific peloidotherapy in patients with degenerative pathology of the lumbar spineAndreea-Alexandra Lupu0Doinita Oprea1Bogdan Obada2Dan Marcel Iliescu3Mihaela Botnarciuc4Ana-Maria Ionescu5Claudia Ileana Mihailov6Madalina-Gabriela Iliescu7Bogdan Marian Caraban8Faculty of Medicine, ‘Ovidius’ University of Constanta, 1 University Alley, Campus – Corp B, 900470 Constanta, Romania; County Emergency Teaching Hospital of Constanta, Tomis Blvd., 900591 Constanta, RomaniaFaculty of Medicine, ‘Ovidius’ University of Constanta, 1 University Alley, Campus – Corp B, 900470 Constanta, Romania; Balneal and Rehabilitation Sanatorium Techirghiol, 34–40 Dr. Victor Climescu Street, 906100 Techirghiol, RomaniaFaculty of Medicine, ‘Ovidius’ University of Constanta, 1 University Alley, Campus – Corp B, 900470 Constanta, Romania; County Emergency Teaching Hospital of Constanta, Tomis Blvd., 900591 Constanta, RomaniaFaculty of Medicine, ‘Ovidius’ University of Constanta, 1 University Alley, Campus – Corp B, 900470 Constanta, RomaniaFaculty of Medicine, ‘Ovidius’ University of Constanta, 1 University Alley, Campus – Corp B, 900470 Constanta, Romania; County Emergency Teaching Hospital of Constanta, Tomis Blvd., 900591 Constanta, RomaniaFaculty of Medicine, ‘Ovidius’ University of Constanta, 1 University Alley, Campus – Corp B, 900470 Constanta, Romania; Railway Clinical Hospital of Constanta, 3-5 First May Blvd., 900123, Constanta, RomaniaFaculty of Medicine, ‘Ovidius’ University of Constanta, 1 University Alley, Campus – Corp B, 900470 Constanta, Romania; Railway Clinical Hospital of Constanta, 3-5 First May Blvd., 900123, Constanta, RomaniaFaculty of Medicine, ‘Ovidius’ University of Constanta, 1 University Alley, Campus – Corp B, 900470 Constanta, Romania; Balneal and Rehabilitation Sanatorium Techirghiol, 34–40 Dr. Victor Climescu Street, 906100 Techirghiol, RomaniaFaculty of Medicine, ‘Ovidius’ University of Constanta, 1 University Alley, Campus – Corp B, 900470 Constanta, Romania; County Emergency Teaching Hospital of Constanta, Tomis Blvd., 900591 Constanta, RomaniaSerotonin is well known to be involved in the mediation of cognitive processes, but also in the regulation of multiple distinct physiological processes, such as pain. It is also involved in the modulation of nociception of the endogenous analgesic system. Among the monoamine neurotransmitters, serotonin plays an important role in signaling chronic pain, hence the importance of its monitoring in lumbar pain due to degenerative pathology, one of the common cause of this kind of pain. The aim of our study is to evaluate the impact of peloidotherapy on the variation of serum serotonin levels in patients with degenerative low back pain. In our study, conducted in Balneal and Rehabilitation Sanatorium of Techirghiol, we evaluated 130 patients who performed balneal and physical treatments for a period of 2 weeks. The patients were divided into 3 groups: 51 patients were enrolled into the hot mud baths group (HMB), 48 in the cold mud baths (CMB) group and 31 in the control group (CG). Each patient performed physiotherapy treatments which includes electrotherapy, massage and kinetotherapy, patients from HMB group had also hot mud therapy and patients from CMB group had cold mud therapy. Serum serotonin was dosed at admission and at discharge, for each patient, and was determined using ELISA method with kits from Demeditec Diagnostics GmbH for human serotonin. All the data from the study were statistically analized using the SPSS 22.0 program, values were interpreted as mean value and standard deviation, and we used ANOVA and t tests. The statistically significant value considered was p<0.05.http://bioclima.ro/Balneo588.pdfserotonindegenerative pathologyumbar spine |
| spellingShingle | Andreea-Alexandra Lupu Doinita Oprea Bogdan Obada Dan Marcel Iliescu Mihaela Botnarciuc Ana-Maria Ionescu Claudia Ileana Mihailov Madalina-Gabriela Iliescu Bogdan Marian Caraban Variation of serum serotonin values under specific peloidotherapy in patients with degenerative pathology of the lumbar spine Balneo and PRM Research Journal serotonin degenerative pathology umbar spine |
| title | Variation of serum serotonin values under specific peloidotherapy in patients with degenerative pathology of the lumbar spine |
| title_full | Variation of serum serotonin values under specific peloidotherapy in patients with degenerative pathology of the lumbar spine |
| title_fullStr | Variation of serum serotonin values under specific peloidotherapy in patients with degenerative pathology of the lumbar spine |
| title_full_unstemmed | Variation of serum serotonin values under specific peloidotherapy in patients with degenerative pathology of the lumbar spine |
| title_short | Variation of serum serotonin values under specific peloidotherapy in patients with degenerative pathology of the lumbar spine |
| title_sort | variation of serum serotonin values under specific peloidotherapy in patients with degenerative pathology of the lumbar spine |
| topic | serotonin degenerative pathology umbar spine |
| url | http://bioclima.ro/Balneo588.pdf |
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