CReVIS-Seq: A highly accurate and multiplexable method for genome-wide mapping of lentiviral integration sites
Lentiviruses have been widely used as a means of transferring exogenous DNAs into human cells to treat various genetic diseases. Lentiviral vectors are fundamentally integrated into the host genome, but their integration sites are generally unpredictable, which may increase the uncertainty for their...
Main Authors: | Heon Seok Kim, Gue-Ho Hwang, Hyomin K. Lee, Taegeun Bae, Seong-Ho Park, Yong Jun Kim, Sun Lee, Jae-Hoon Park, Sangsu Bae, Junho K. Hur |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-03-01
|
Series: | Molecular Therapy: Methods & Clinical Development |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2329050120302163 |
Similar Items
-
Extru-seq: a method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approaches
by: Jeonghun Kwon, et al.
Published: (2023-01-01) -
Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase
by: DuPage, Michel J., et al.
Published: (2014) -
The use of lentiviral vectors and Cre/loxP to investigate the function of genes in complex behaviors
by: Scott Heldt, et al.
Published: (2009-11-01) -
Current trends in gene recovery mediated by the CRISPR-Cas system
by: Hyeon-Ki Jang, et al.
Published: (2020-07-01) -
Ectopic transient overexpression of facilitates BMP4-induced osteogenic transdifferentiation of human umbilical vein endothelial cells
by: Seung Hyun L Kim, et al.
Published: (2020-03-01)