Role of endoscopic ultrasound-guided fine-needle aspiration in adrenal lesions: analysis of 32 patients
Objective: Endoscopic ultrasound-guided fine-needle aspiration cytology (EUS-FNAC) is a precise and safe technique that provides both radiological and pathological diagnosis with a better diagnostic yield and minimal adverse events. EUS-FNAC led to the remarkable increase in the detection rate of in...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Journal of Cytology |
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| Online Access: | http://www.jcytol.org/article.asp?issn=0970-9371;year=2018;volume=35;issue=2;spage=83;epage=89;aulast=Gupta |
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| author | Rakesh K Gupta Kaushik Majumdar Ravindra K Saran Siddharth Srivastava Puja Sakhuja Vineeta V Batra |
| author_facet | Rakesh K Gupta Kaushik Majumdar Ravindra K Saran Siddharth Srivastava Puja Sakhuja Vineeta V Batra |
| author_sort | Rakesh K Gupta |
| collection | DOAJ |
| description | Objective: Endoscopic ultrasound-guided fine-needle aspiration cytology (EUS-FNAC) is a precise and safe technique that provides both radiological and pathological diagnosis with a better diagnostic yield and minimal adverse events. EUS-FNAC led to the remarkable increase in the detection rate of incidentaloma found during radiologic staging or follow-up in various malignancy or unrelated conditions. Aims: We did this preliminary study with an aim to evaluate the role of EUS-FNA in diagnosing and classifying adrenal lesions, clinical impact, and compare the outcome with the previously published literature. Materials and Methods: We included 32 consecutive cases (both retrospective and prospective) of EUS-guided adrenal aspirate performed over a period of 3.3 years. The indications for the aspirate in decreasing order were metastasis (most common carcinoma gall bladder) > primary adrenal mass > disseminated tuberculosis > pyrexia of unknown origin. On EUS, 28 cases revealed space occupying lesion or mass (two cases bilateral) and four cases revealed diffuse enlargement (two cases bilateral) with a mean size of 21 mm. Results: The cytology reports were benign adrenal aspirate (43.8%), metastatic adenocarcinoma (15.6%), histoplasmosis (9.4%), tuberculosis (9.4%), round cell tumor (6.2%), adrenocortical carcinoma (3.1%), and descriptive (3.1%). Three cases (9.4%) yielded inadequate sample. The TNM staging was altered in 22.23% of the cases by result of adrenal aspirate. Conclusions: EUS-FNA of the adrenal gland is a safe, quick, and sensitive and real-time diagnostic technique, which requires an integrated approach of clinician, endoscopist, and cytopathologist for high precision in diagnosis. Although the role of EUS-FNA for right adrenal is not much described, we found adequate sample yield in all the four patients that underwent the procedure. |
| first_indexed | 2024-04-12T06:02:24Z |
| format | Article |
| id | doaj.art-208f6ade19004384bddd2521face85a3 |
| institution | Directory Open Access Journal |
| issn | 0970-9371 |
| language | English |
| last_indexed | 2024-04-12T06:02:24Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Cytology |
| spelling | doaj.art-208f6ade19004384bddd2521face85a32022-12-22T03:44:59ZengWolters Kluwer Medknow PublicationsJournal of Cytology0970-93712018-01-01352838910.4103/JOC.JOC_241_16Role of endoscopic ultrasound-guided fine-needle aspiration in adrenal lesions: analysis of 32 patientsRakesh K GuptaKaushik MajumdarRavindra K SaranSiddharth SrivastavaPuja SakhujaVineeta V BatraObjective: Endoscopic ultrasound-guided fine-needle aspiration cytology (EUS-FNAC) is a precise and safe technique that provides both radiological and pathological diagnosis with a better diagnostic yield and minimal adverse events. EUS-FNAC led to the remarkable increase in the detection rate of incidentaloma found during radiologic staging or follow-up in various malignancy or unrelated conditions. Aims: We did this preliminary study with an aim to evaluate the role of EUS-FNA in diagnosing and classifying adrenal lesions, clinical impact, and compare the outcome with the previously published literature. Materials and Methods: We included 32 consecutive cases (both retrospective and prospective) of EUS-guided adrenal aspirate performed over a period of 3.3 years. The indications for the aspirate in decreasing order were metastasis (most common carcinoma gall bladder) > primary adrenal mass > disseminated tuberculosis > pyrexia of unknown origin. On EUS, 28 cases revealed space occupying lesion or mass (two cases bilateral) and four cases revealed diffuse enlargement (two cases bilateral) with a mean size of 21 mm. Results: The cytology reports were benign adrenal aspirate (43.8%), metastatic adenocarcinoma (15.6%), histoplasmosis (9.4%), tuberculosis (9.4%), round cell tumor (6.2%), adrenocortical carcinoma (3.1%), and descriptive (3.1%). Three cases (9.4%) yielded inadequate sample. The TNM staging was altered in 22.23% of the cases by result of adrenal aspirate. Conclusions: EUS-FNA of the adrenal gland is a safe, quick, and sensitive and real-time diagnostic technique, which requires an integrated approach of clinician, endoscopist, and cytopathologist for high precision in diagnosis. Although the role of EUS-FNA for right adrenal is not much described, we found adequate sample yield in all the four patients that underwent the procedure.http://www.jcytol.org/article.asp?issn=0970-9371;year=2018;volume=35;issue=2;spage=83;epage=89;aulast=GuptaAdrenalendoscopic ultrasoundfine needle aspiration cytologyincidentaloma |
| spellingShingle | Rakesh K Gupta Kaushik Majumdar Ravindra K Saran Siddharth Srivastava Puja Sakhuja Vineeta V Batra Role of endoscopic ultrasound-guided fine-needle aspiration in adrenal lesions: analysis of 32 patients Journal of Cytology Adrenal endoscopic ultrasound fine needle aspiration cytology incidentaloma |
| title | Role of endoscopic ultrasound-guided fine-needle aspiration in adrenal lesions: analysis of 32 patients |
| title_full | Role of endoscopic ultrasound-guided fine-needle aspiration in adrenal lesions: analysis of 32 patients |
| title_fullStr | Role of endoscopic ultrasound-guided fine-needle aspiration in adrenal lesions: analysis of 32 patients |
| title_full_unstemmed | Role of endoscopic ultrasound-guided fine-needle aspiration in adrenal lesions: analysis of 32 patients |
| title_short | Role of endoscopic ultrasound-guided fine-needle aspiration in adrenal lesions: analysis of 32 patients |
| title_sort | role of endoscopic ultrasound guided fine needle aspiration in adrenal lesions analysis of 32 patients |
| topic | Adrenal endoscopic ultrasound fine needle aspiration cytology incidentaloma |
| url | http://www.jcytol.org/article.asp?issn=0970-9371;year=2018;volume=35;issue=2;spage=83;epage=89;aulast=Gupta |
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