Association of CD47 Expression with Clinicopathologic Characteristics and Survival Outcomes in Muscle Invasive Bladder Cancer

Association of CD47 Expression with Clinicopathologic Characteristics and Survival Outcomes in Muscle Invasive Bladder Cancer

Objective: CD47 is an antiphagocytic molecule that plays a critical role in immune surveillance. A variety of malignancies have been shown to evade the immune system by increasing the expression of CD47 on the cell surface. As a result, anti-CD47 therapy is under clinical investigation for a subset...

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Bibliographic Details
Main Authors: Zin W. Myint, Zena Chahine, Rani Jayswal, Emily Bachert, Robert J. McDonald, Stephen E. Strup, Andrew C. James, Patrick J. Hensley, Derek B. Allison
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Journal of Personalized Medicine
Subjects:
muscle invasive bladder cancer
CD47 expression
neoadjuvant therapy
biomarker
Online Access:https://www.mdpi.com/2075-4426/13/6/885

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