Targeting T cell metabolism in the tumor microenvironment: an anti-cancer therapeutic strategy

Targeting T cell metabolism in the tumor microenvironment: an anti-cancer therapeutic strategy

Abstract T cells play important roles in anti-tumor immunity. Emerging evidence has revealed that distinct metabolic changes impact the activation and differentiation of T cells. Tailoring immune responses by manipulating cellular metabolic pathways and the identification of new targets may provide...

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Bibliographic Details
Main Authors: Zhongping Yin, Ling Bai, Wei Li, Tanlun Zeng, Huimin Tian, Jiuwei Cui
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
T cell
Immunotherapy
Cancer
Metabolic reprogramming
Online Access:http://link.springer.com/article/10.1186/s13046-019-1409-3

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