The role of the e3 ligase cbl-B in murine dendritic cells.

Dendritic cells (DCs) are potent antigen-presenting cells with a promising potential in cancer immunotherapy. Cbl proteins are E3 ubiquitin ligases and have been implicated in regulating the functional activity of various immune cells. As an example, c-Cbl negatively affects DC activation. We here d...

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Hlavní autoři: Stephanie Wallner, Christina Lutz-Nicoladoni, Christoph H Tripp, Günther Gastl, Gottfried Baier, Josef M Penninger, Patrizia Stoitzner, Dominik Wolf
Médium: Článek
Jazyk:English
Vydáno: Public Library of Science (PLoS) 2013-01-01
Edice:PLoS ONE
On-line přístup:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23762309/pdf/?tool=EBI