Supervivencia en las personas que viven con VIH en el marco del sistema de salud colombiano 2011-2018
Objective: to describe the seven-year survival and predictors of mortality among people with HIV who were treated in the Colombian health system between 2011 and 2018.Methods: 64 039 people diagnosed with HIV in Colombia were included. Kaplan-Meier analysis estimated the probability of survival from...
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| Format: | Article |
| Language: | English |
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Asociación Colombiana de Infectología
2021-04-01
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| Series: | Infectio |
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| _version_ | 1811274320527228928 |
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| author | Nathaly Ramírez-García |
| author_facet | Nathaly Ramírez-García |
| author_sort | Nathaly Ramírez-García |
| collection | DOAJ |
| description | Objective: to describe the seven-year survival and predictors of mortality among people with HIV who were treated in the Colombian health system between 2011 and 2018.Methods: 64 039 people diagnosed with HIV in Colombia were included. Kaplan-Meier analysis estimated the probability of survival from the date of diagnosis. A Royston Parmar flexible parametric survival model was fitted.Results: The overall survival at 7 years was 94.8% (95% CI: 94.5-95.2). Survival was related to sex (men, HR: 1.2; 95% CI: 1.1-1.4; p: 0.010); people ≥50 years of age (HR: 3.1; 95% CI: 1.6-6.3; p: 0.002); subsidized regime (HR: 2.2; 95% CI: 1.9-2.5; p: <0.001); AIDS stage (HR: 2.8; 95% CI: 2.1-3.7; p: <0.001); a detectable viral load (HR: 7.1; 95% CI: 6.0-8.3; p: <0.001); and a CD4+ Lymphocyte count <350 cells/μL (HR: 1.9; 95% CI: 1.4-2.4; p: <0.001).Conclusion: The probability of survival of people living with HIV increases when they are diagnosed at a young age, in those with a CD4+ T Lymphocyte count ≥350 cells/μL, an undetectable viral load (<50 copies/mL) and are not in the AIDS stage. |
| first_indexed | 2024-04-12T23:16:54Z |
| format | Article |
| id | doaj.art-209d4db9ece3442abcb4033b365c3723 |
| institution | Directory Open Access Journal |
| issn | 0123-9392 |
| language | English |
| last_indexed | 2024-04-12T23:16:54Z |
| publishDate | 2021-04-01 |
| publisher | Asociación Colombiana de Infectología |
| record_format | Article |
| series | Infectio |
| spelling | doaj.art-209d4db9ece3442abcb4033b365c37232022-12-22T03:12:39ZengAsociación Colombiana de InfectologíaInfectio0123-93922021-04-01254276283https://doi.org/10.22354/in.v25i4.960Supervivencia en las personas que viven con VIH en el marco del sistema de salud colombiano 2011-2018Nathaly Ramírez-García0https://orcid.org/0000-0002-1358-619XCuenta de Alto Costo- Fondo Colombiano de Enfermedades de Alto Costo, Bogotá, D.C., ColombiaObjective: to describe the seven-year survival and predictors of mortality among people with HIV who were treated in the Colombian health system between 2011 and 2018.Methods: 64 039 people diagnosed with HIV in Colombia were included. Kaplan-Meier analysis estimated the probability of survival from the date of diagnosis. A Royston Parmar flexible parametric survival model was fitted.Results: The overall survival at 7 years was 94.8% (95% CI: 94.5-95.2). Survival was related to sex (men, HR: 1.2; 95% CI: 1.1-1.4; p: 0.010); people ≥50 years of age (HR: 3.1; 95% CI: 1.6-6.3; p: 0.002); subsidized regime (HR: 2.2; 95% CI: 1.9-2.5; p: <0.001); AIDS stage (HR: 2.8; 95% CI: 2.1-3.7; p: <0.001); a detectable viral load (HR: 7.1; 95% CI: 6.0-8.3; p: <0.001); and a CD4+ Lymphocyte count <350 cells/μL (HR: 1.9; 95% CI: 1.4-2.4; p: <0.001).Conclusion: The probability of survival of people living with HIV increases when they are diagnosed at a young age, in those with a CD4+ T Lymphocyte count ≥350 cells/μL, an undetectable viral load (<50 copies/mL) and are not in the AIDS stage.survival analysishivcd4 lymphocyte countviral load |
| spellingShingle | Nathaly Ramírez-García Supervivencia en las personas que viven con VIH en el marco del sistema de salud colombiano 2011-2018 Infectio survival analysis hiv cd4 lymphocyte count viral load |
| title | Supervivencia en las personas que viven con VIH en el marco del sistema de salud colombiano 2011-2018 |
| title_full | Supervivencia en las personas que viven con VIH en el marco del sistema de salud colombiano 2011-2018 |
| title_fullStr | Supervivencia en las personas que viven con VIH en el marco del sistema de salud colombiano 2011-2018 |
| title_full_unstemmed | Supervivencia en las personas que viven con VIH en el marco del sistema de salud colombiano 2011-2018 |
| title_short | Supervivencia en las personas que viven con VIH en el marco del sistema de salud colombiano 2011-2018 |
| title_sort | supervivencia en las personas que viven con vih en el marco del sistema de salud colombiano 2011 2018 |
| topic | survival analysis hiv cd4 lymphocyte count viral load |
| work_keys_str_mv | AT nathalyramirezgarcia supervivenciaenlaspersonasquevivenconvihenelmarcodelsistemadesaludcolombiano20112018 |