Legionnaires' Disease

Legionnaires’ disease is a severe form of pneumonia caused by Legionella species which are ubiquitous in both natural and man-made environments. It causes high morbidity and case fatality rates. The disease is acquired by aspiration of water or inhalation of aerosols containing the bacteria from env...

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Main Author: Haluk Erdoğan
Format: Article
Language:Turkish
Published: Galenos Yayinevi 2018-12-01
Series:Mediterranean Journal of Infection, Microbes and Antimicrobials
Subjects:
Online Access:http://mjima.org/text.php?&id=105
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author Haluk Erdoğan
author_facet Haluk Erdoğan
author_sort Haluk Erdoğan
collection DOAJ
description Legionnaires’ disease is a severe form of pneumonia caused by Legionella species which are ubiquitous in both natural and man-made environments. It causes high morbidity and case fatality rates. The disease is acquired by aspiration of water or inhalation of aerosols containing the bacteria from environmental sources. Early diagnosis and appropriate treatment are important factors in determining the prognosis. Clinical and laboratory predictors will not reliably identify cases of Legionnaires’ disease; therefore, the diagnosis requires specific laboratory tests. Legionnaires’ disease is diagnosed by culture, Legionella urinary antigenuria, polymerase chain reaction, or serologic analyses. Isolation of Legionella from clinical samples is the gold standard. Legionella urinary antigen tests are easy and useful for early diagnosis of Legionnaires’ disease. Fluoroquinolones, macrolides, and doxycycline are drugs of choice. Legionnaires’ disease is considered to be preventable illness since it is possible to control and remove the bacteria in reservoirs. In Turkey, travel-associated Legionnaires’ disease has a specific surveillance program since 1996. After the year of 2015, it became mandatory to take annual water cultures for Legionella from hospital water systems. The aim of this review is to raise awareness of legionellosis and to summarize the current literature.
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spelling doaj.art-20a37a015b4d4c5eaec0b463fe8d257b2023-02-15T16:08:52ZturGalenos YayineviMediterranean Journal of Infection, Microbes and Antimicrobials2147-673X2018-12-01710.4274/mjima.2018.2Legionnaires' DiseaseHaluk Erdoğan0Başkent University Alanya Medical and Research Center, Department of Infectious Diseases and Clinical Microbiology, Alanya, TurkeyLegionnaires’ disease is a severe form of pneumonia caused by Legionella species which are ubiquitous in both natural and man-made environments. It causes high morbidity and case fatality rates. The disease is acquired by aspiration of water or inhalation of aerosols containing the bacteria from environmental sources. Early diagnosis and appropriate treatment are important factors in determining the prognosis. Clinical and laboratory predictors will not reliably identify cases of Legionnaires’ disease; therefore, the diagnosis requires specific laboratory tests. Legionnaires’ disease is diagnosed by culture, Legionella urinary antigenuria, polymerase chain reaction, or serologic analyses. Isolation of Legionella from clinical samples is the gold standard. Legionella urinary antigen tests are easy and useful for early diagnosis of Legionnaires’ disease. Fluoroquinolones, macrolides, and doxycycline are drugs of choice. Legionnaires’ disease is considered to be preventable illness since it is possible to control and remove the bacteria in reservoirs. In Turkey, travel-associated Legionnaires’ disease has a specific surveillance program since 1996. After the year of 2015, it became mandatory to take annual water cultures for Legionella from hospital water systems. The aim of this review is to raise awareness of legionellosis and to summarize the current literature.http://mjima.org/text.php?&id=105Legionnaires’ diseaseLegionella pneumophilaLegionella spp.
spellingShingle Haluk Erdoğan
Legionnaires' Disease
Mediterranean Journal of Infection, Microbes and Antimicrobials
Legionnaires’ disease
Legionella pneumophila
Legionella spp.
title Legionnaires' Disease
title_full Legionnaires' Disease
title_fullStr Legionnaires' Disease
title_full_unstemmed Legionnaires' Disease
title_short Legionnaires' Disease
title_sort legionnaires disease
topic Legionnaires’ disease
Legionella pneumophila
Legionella spp.
url http://mjima.org/text.php?&id=105
work_keys_str_mv AT halukerdogan legionnairesdisease