Myeloid sarcoma of submandibular salivary gland

Objective: To report a rare case of a myeloid sarcoma of submandibular salivary gland. Methods: A 65-year-old woman with a history of successfully treated myelodysplastic syndrome, presenting with periodic painful swelling of her right submandibular area. Results: Physical evaluation, ultrasound and...

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Main Authors: Federico Dagna, Pamela Giordano, Valeria Boggio, Roberto Albera
Format: Article
Language:English
Published: SAGE Publishing 2016-01-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X15625016
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author Federico Dagna
Pamela Giordano
Valeria Boggio
Roberto Albera
author_facet Federico Dagna
Pamela Giordano
Valeria Boggio
Roberto Albera
author_sort Federico Dagna
collection DOAJ
description Objective: To report a rare case of a myeloid sarcoma of submandibular salivary gland. Methods: A 65-year-old woman with a history of successfully treated myelodysplastic syndrome, presenting with periodic painful swelling of her right submandibular area. Results: Physical evaluation, ultrasound and CT scan revealed the presence of a 3-cm mass contiguous to the submandibular salivary gland. A core needle biopsy confirmed the diagnosis of myeloid sarcoma. Bone marrow biopsy was still showing complete remission and the submandibular gland was the only extramedullary site involved. The patient was submitted to chemotherapy. Conclusion: Myeloid sarcoma is a rare extramedullary neoplasm. It can virtually involve any anatomic site, but it usually involves lymph nodes, paranasal sinuses, skin, soft tissue and periostium. Myeloid sarcomas of salivary glands are very rare and ENTs should be aware of this disease in order to include it in the differential diagnosis of a solitary neck mass.
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spelling doaj.art-20a49ba83af5441c91e3fc1f561790b92022-12-21T19:49:14ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2016-01-01410.1177/2050313X1562501610.1177_2050313X15625016Myeloid sarcoma of submandibular salivary glandFederico DagnaPamela GiordanoValeria BoggioRoberto AlberaObjective: To report a rare case of a myeloid sarcoma of submandibular salivary gland. Methods: A 65-year-old woman with a history of successfully treated myelodysplastic syndrome, presenting with periodic painful swelling of her right submandibular area. Results: Physical evaluation, ultrasound and CT scan revealed the presence of a 3-cm mass contiguous to the submandibular salivary gland. A core needle biopsy confirmed the diagnosis of myeloid sarcoma. Bone marrow biopsy was still showing complete remission and the submandibular gland was the only extramedullary site involved. The patient was submitted to chemotherapy. Conclusion: Myeloid sarcoma is a rare extramedullary neoplasm. It can virtually involve any anatomic site, but it usually involves lymph nodes, paranasal sinuses, skin, soft tissue and periostium. Myeloid sarcomas of salivary glands are very rare and ENTs should be aware of this disease in order to include it in the differential diagnosis of a solitary neck mass.https://doi.org/10.1177/2050313X15625016
spellingShingle Federico Dagna
Pamela Giordano
Valeria Boggio
Roberto Albera
Myeloid sarcoma of submandibular salivary gland
SAGE Open Medical Case Reports
title Myeloid sarcoma of submandibular salivary gland
title_full Myeloid sarcoma of submandibular salivary gland
title_fullStr Myeloid sarcoma of submandibular salivary gland
title_full_unstemmed Myeloid sarcoma of submandibular salivary gland
title_short Myeloid sarcoma of submandibular salivary gland
title_sort myeloid sarcoma of submandibular salivary gland
url https://doi.org/10.1177/2050313X15625016
work_keys_str_mv AT federicodagna myeloidsarcomaofsubmandibularsalivarygland
AT pamelagiordano myeloidsarcomaofsubmandibularsalivarygland
AT valeriaboggio myeloidsarcomaofsubmandibularsalivarygland
AT robertoalbera myeloidsarcomaofsubmandibularsalivarygland