Nontargeted metabolomics to characterize the effects of isotretinoin on skin metabolism in rabbit with acne

Nontargeted metabolomics to characterize the effects of isotretinoin on skin metabolism in rabbit with acne

Background: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit. This study aimed to explore the pathogenesis of acne and the therapeutic mechanism of isotretinoin from the metabolic perspective in coal tar-induced acne in rabbits.Methods: Ultra-high performance liquid chromato...

Full description

Bibliographic Details
Main Authors:	Xiao-Liang Ou-Yang, Deng Zhang, Xiu-Ping Wang, Si-Min Yu, Zhen Xiao, Wei Li, Chun-Ming Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Series:	Frontiers in Pharmacology
Subjects:	acne vulgaris metabolomics isotretinoin UHPLC-QTOF-MS animal model
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.963472/full

Similar Items

A systematic review of isotretinoin dosing in acne vulgaris
by: Aoife U. Daly, et al.
Published: (2023-09-01)

Assessment of Hematological and Inflammatory Parameters in Patients Receiving Isotretinoin Therapy for Acne Vulgaris
by: Mahizer Yaldız, et al.
Published: (2018-09-01)

The effects of isotretinoin on the inner ear in patients with acne vulgaris
by: Esra İnan Doğan, et al.
Published: (2022-03-01)

Efficacy of Isotretinoin in The Management of Enlarged Facial Pores in Moderate and Severe Acne Vulgaris Patients
by: Waleed Gaber, et al.
Published: (2023-08-01)

Severe Nodulocystic Acne not Responding to Isotretinoin Therapy Successfully Treated with Oral Dapsone
by: Lutfi Al-Kathiri, et al.
Published: (2018-09-01)

Pseudo-acne fulminans associated with oral isotretinoin
by: Luciana Rosa Grando, et al.
Published: (2014-07-01)

Experiência de 65 anos no tratamento da acne e de 26 anos com isotretinoína oral A 65-year experience treating acne, including 26 years with oral isotretinoin
by: Sebastião de Almeida Prado Sampaio, et al.
Published: (2008-08-01)

Non-antibiotic Isotretinoin Treatment Differentially Controls Propionibacterium acnes on Skin of Acne Patients
by: Angela E. Ryan-Kewley, et al.
Published: (2017-07-01)

Sacroiliitis after use of oral isotretinoin - association with acne fulminans or adverse effect?
by: Ariane Silva Bastos Geller, et al.
Published: (2013-12-01)

UHPLC-qTOF-MS-Based Nontargeted Metabolomics to Characterize the Effects of Capsaicin on Plasma and Skin Metabolic Profiles of C57BL/6 Mice-An In vivo Experimental Study
by: Xiao Z, et al.
Published: (2024-03-01)

Avaliação dos efeitos adversos clínicos e alterações laboratoriais em pacientes com acne vulgar tratados com isotretinoína oral Evaluation of clinical adverse effects and laboratory alterations in patients with acne vulgaris treated with oral isotretinoin
by: Maria de Fátima de Medeiros Brito, et al.
Published: (2010-06-01)

Elevated creatine kinase levels, exercise, and isotretinoin for acne
by: Justin W. Marson, MD, et al.
Published: (2022-03-01)

Effect of oral isotretinoin therapy on thyroid function in patients with moderate-to-severe acne vulgaris: A prospective study
by: Fahad AlSaif, et al.
Published: (2020-01-01)

Lactobacillus plantarum MH-301 as an effective adjuvant to isotretinoin in the treatment of acne vulgaris: a randomized and open-label trail
by: Lili Liang, et al.
Published: (2024-01-01)

Development of acute sacroiliitis due to the use of oral isotretinoin in patients with acne vulgaris: Four case presentation
by: Özlem Karadağ Köse, et al.
Published: (2017-11-01)

Minimize the regular laboratory monitoring during the systemic isotretinoin treatment: data of 704 patients with acne vulgaris
by: Ayşe Öktem, et al.
Published: (2019-11-01)

Analysis of blood lipid in 89 acne patients with oral isotretinoin
by: Danyi HUANG, et al.
Published: (2021-12-01)

Evaluation of the Effect of Oral Isotretinoin on the Level of Serum YKL40 in Acne Vulgaris Patients: A Cross-Sectional Case-Control
by: Ali MA, et al.
Published: (2023-11-01)

Altered Gene Expression in Acne Vulgaris Patients Treated by Oral Isotretinoin: A Preliminary Study
by: Jiang Y, et al.
Published: (2020-09-01)

Acne vulgaris - review on pathogenesis and treatment
by: Bartłomiej Żmuda, et al.
Published: (2024-01-01)

Isotretinoin treatment and risk of depression in acne vulgar patient: what is the evidence?
by: Diana Santos, et al.
Published: (2022-07-01)

Efficacy and Safety of Combined Isotretinoin and Azithromycin for Treatment of Severe Nodulocystic Acne
by: Samer A. Dhaher, et al.
Published: (2016-12-01)

Evaluation of the Incidence of Anal Fissures in Patients Who Systemic Isotretinoin Therapy for Acne
by: Hamza Aktaş, et al.
Published: (2023-07-01)

The effects of isotretinoin on affective and cognitive functions are disparate in adolescent acne vulgaris patients
by: Aysenur Botsali, et al.
Published: (2020-10-01)

Is oral isotretinoin treatment contraindicated for patients with known peanut allergies?
by: Victoria S. Humphrey, BS, et al.
Published: (2020-02-01)

The weeks and the cumulative doses of the first adverse events related to oral isotretinoin in acne patients: analysis of 300 patients
by: Duriye Deniz Demirseren, et al.
Published: (2017-05-01)

A randomized comparative trial of two low-dose oral isotretinoin regimens in moderate to severe acne vulgaris
by: Daulat Ram Dhaked, et al.
Published: (2016-01-01)

Facial hypertrichosis after isotretinoin therapy: Is it a side effect or coincidence?
by: Esra Saraç, et al.
Published: (2022-03-01)

To the question of the effect of isotretinoin on the neuropsychic state of patients with acne
by: Alexey V. Samtsov
Published: (2023-07-01)

Evaluating the Role of Omega 3 on the Side Effects of Isotretinoin in Patients with the Acnea Vulgaris
by: Mina Mirnezami
Published: (2017-01-01)

Acne fulminans in the course of oral isotretinoin treatment. Presentation of cases
by: Magdalena Kręgiel, et al.
Published: (2017-04-01)

Difficulties in the treatment of acne fulminans – case report
by: Dorota Kozłowska, et al.
Published: (2015-06-01)

Isotretinoin for acne vulgaris – an update on adverse effects and laboratory monitoring
by: Haady Fallah, et al.
Published: (2022-07-01)

Efficacy of Topical 0.05% Isotretinoin Gel Versus 0.1% Adapalene Gel in The Treatment of Mild to Moderate Acne Vulgaris
by: Summaya Saleem, et al.
Published: (2023-02-01)

Effect of systemic isotretinoin therapy on semen parameters
by: Abdullah Gurel, et al.
Published: (2023-12-01)

A common but not well-known cause in anal fissure development and treatment failure: Isotretinoin treatment for acne vulgaris
by: Pelin Basim, et al.
Published: (2020-12-01)

Effects of systemic isotretinoin treatment on hemogram, biochemical parameters, and inflammatory markers
by: Işıl Deniz Oğuz, et al.
Published: (2024-03-01)

The impact of oral isotretinoin on ovarian functions of acne patients complaining of polycystic ovarian syndrome: a prospective study
by: Heba I. Elnagar, et al.
Published: (2024-01-01)

Efficacy of fixed daily 20 mg of isotretinoin in moderate to severe scar prone acne
by: Abbas Rasi, et al.
Published: (2014-01-01)

The effects of Isotretinoin on serum levels of creatine phosphokinase and musculoskeletal symptoms in patients with acne vulgaris
by: Azizzadeh M, et al.
Published: (2011-08-01)