Changes in the rest-activity rhythm in migraine patients are associated with anxiety symptoms
Objective: To characterize rest-activity rhythm in chronic migraine (CM) and to investigate the relationship between this rhythm and depressive and anxiety symptoms in patients with CM. Methods: This was a study of adults aged 20 to 40 years. The rest-activity rhythm of patients with CM (n=23) and...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Associação Brasileira de Psiquiatria (ABP)
2022-10-01
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| Series: | Brazilian Journal of Psychiatry |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462022005011201&tlng=en |
| _version_ | 1797985908407926784 |
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| author | Mírian C.M.M. David Marina S.B. Mattos Jandirlly J.S. Souto Sarah A.C.F. Brito Etcheverry S. Leite Eduardo N. Valença Gilma S. Galdino Patrick G.G. Sampaio Daniel M.C. Moura Mário A.L. Miguel John F. Araújo Carlúcia I.F. Franco Rhowena J.B. Matos |
| author_facet | Mírian C.M.M. David Marina S.B. Mattos Jandirlly J.S. Souto Sarah A.C.F. Brito Etcheverry S. Leite Eduardo N. Valença Gilma S. Galdino Patrick G.G. Sampaio Daniel M.C. Moura Mário A.L. Miguel John F. Araújo Carlúcia I.F. Franco Rhowena J.B. Matos |
| author_sort | Mírian C.M.M. David |
| collection | DOAJ |
| description | Objective: To characterize rest-activity rhythm in chronic migraine (CM) and to investigate the relationship between this rhythm and depressive and anxiety symptoms in patients with CM. Methods: This was a study of adults aged 20 to 40 years. The rest-activity rhythm of patients with CM (n=23) and non-headache controls (NH, n=23) was assessed by actigraphy for 15 days, and they completed the following assessments: Visual Analogue Scale for pain intensity; Headache Diary; Headache Impact Test-6; Morningness-Eveningness Questionnaire; Pittsburgh Sleep Quality Index; Epworth Sleepiness Scale; Beck Depression Inventory; and State-Trait Anxiety Inventory. Results: Patients with CM showed less activity over 24 hours and more fragmented sleep. Reduced interdaily stability of the rest-activity rhythm was observed, with less robustness of this rhythm in the CM group. Multiple linear regressions revealed a significant association between the rest-activity rhythm and trait anxiety variables in patients with CM, specifically regarding the relative amplitude of the cycle, activity throughout 24 hours and during sleep, and robustness of the rest-activity rhythm. Conclusions: Our findings provide evidence that the robustness of the rest-activity rhythm, activity throughout 24 hours, and sleep fragmentation are associated with trait anxiety in patients with CM. Clinical trial registration: Brazilian Clinical Trials Registry (registration number: RBR-4M5J4S). |
| first_indexed | 2024-04-11T07:25:05Z |
| format | Article |
| id | doaj.art-20ae2c1038494e47926889430f646db9 |
| institution | Directory Open Access Journal |
| issn | 1809-452X |
| language | English |
| last_indexed | 2024-04-11T07:25:05Z |
| publishDate | 2022-10-01 |
| publisher | Associação Brasileira de Psiquiatria (ABP) |
| record_format | Article |
| series | Brazilian Journal of Psychiatry |
| spelling | doaj.art-20ae2c1038494e47926889430f646db92022-12-22T04:37:06ZengAssociação Brasileira de Psiquiatria (ABP)Brazilian Journal of Psychiatry1809-452X2022-10-0110.47626/1516-4446-2021-2367Changes in the rest-activity rhythm in migraine patients are associated with anxiety symptomsMírian C.M.M. Davidhttps://orcid.org/0000-0002-7152-8852Marina S.B. Mattoshttps://orcid.org/0000-0002-4445-0754Jandirlly J.S. Soutohttps://orcid.org/0000-0003-1746-332XSarah A.C.F. BritoEtcheverry S. LeiteEduardo N. ValençaGilma S. Galdinohttps://orcid.org/0000-0001-8644-5251Patrick G.G. Sampaiohttps://orcid.org/0000-0003-0952-9798Daniel M.C. MouraMário A.L. Miguelhttps://orcid.org/0000-0002-7248-3529John F. Araújohttps://orcid.org/0000-0002-8022-2425Carlúcia I.F. Francohttps://orcid.org/0000-0001-6653-8864Rhowena J.B. Matoshttps://orcid.org/0000-0001-5914-7304 Objective: To characterize rest-activity rhythm in chronic migraine (CM) and to investigate the relationship between this rhythm and depressive and anxiety symptoms in patients with CM. Methods: This was a study of adults aged 20 to 40 years. The rest-activity rhythm of patients with CM (n=23) and non-headache controls (NH, n=23) was assessed by actigraphy for 15 days, and they completed the following assessments: Visual Analogue Scale for pain intensity; Headache Diary; Headache Impact Test-6; Morningness-Eveningness Questionnaire; Pittsburgh Sleep Quality Index; Epworth Sleepiness Scale; Beck Depression Inventory; and State-Trait Anxiety Inventory. Results: Patients with CM showed less activity over 24 hours and more fragmented sleep. Reduced interdaily stability of the rest-activity rhythm was observed, with less robustness of this rhythm in the CM group. Multiple linear regressions revealed a significant association between the rest-activity rhythm and trait anxiety variables in patients with CM, specifically regarding the relative amplitude of the cycle, activity throughout 24 hours and during sleep, and robustness of the rest-activity rhythm. Conclusions: Our findings provide evidence that the robustness of the rest-activity rhythm, activity throughout 24 hours, and sleep fragmentation are associated with trait anxiety in patients with CM. Clinical trial registration: Brazilian Clinical Trials Registry (registration number: RBR-4M5J4S).http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462022005011201&tlng=enChronic migrainesleepcircadian rhythmanxietydepression |
| spellingShingle | Mírian C.M.M. David Marina S.B. Mattos Jandirlly J.S. Souto Sarah A.C.F. Brito Etcheverry S. Leite Eduardo N. Valença Gilma S. Galdino Patrick G.G. Sampaio Daniel M.C. Moura Mário A.L. Miguel John F. Araújo Carlúcia I.F. Franco Rhowena J.B. Matos Changes in the rest-activity rhythm in migraine patients are associated with anxiety symptoms Brazilian Journal of Psychiatry Chronic migraine sleep circadian rhythm anxiety depression |
| title | Changes in the rest-activity rhythm in migraine patients are associated with anxiety symptoms |
| title_full | Changes in the rest-activity rhythm in migraine patients are associated with anxiety symptoms |
| title_fullStr | Changes in the rest-activity rhythm in migraine patients are associated with anxiety symptoms |
| title_full_unstemmed | Changes in the rest-activity rhythm in migraine patients are associated with anxiety symptoms |
| title_short | Changes in the rest-activity rhythm in migraine patients are associated with anxiety symptoms |
| title_sort | changes in the rest activity rhythm in migraine patients are associated with anxiety symptoms |
| topic | Chronic migraine sleep circadian rhythm anxiety depression |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462022005011201&tlng=en |
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