Relationship between CAINS negative symptoms and cognition, psychosocial functioning and quality of life in patients with a first psychotic episode of schizophrenia
Introduction Negative symptoms has been classically associated with cognition, psychosocial functioning and quality of life in patients with schizophrenia. But negative symptoms are not a unitary construct, encompassing two different factors: diminished expression, and motivation and pleasure. Few...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2023-03-01
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| Series: | European Psychiatry |
| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933823013342/type/journal_article |
| _version_ | 1797617260909559808 |
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| author | R. Rodriguez-Jimenez L. García-Fernández V. Romero-Ferreiro M. Valtueña García A. I. Aparicio J. M. Espejo-Saavedra L. Sánchez-Pastor A. Nuñez-Doyle M. Dompablo O. Jiménez-Rodríguez D. Rentero P. Fernández-Sotos I. Martínez-Gras J. L. Santos |
| author_facet | R. Rodriguez-Jimenez L. García-Fernández V. Romero-Ferreiro M. Valtueña García A. I. Aparicio J. M. Espejo-Saavedra L. Sánchez-Pastor A. Nuñez-Doyle M. Dompablo O. Jiménez-Rodríguez D. Rentero P. Fernández-Sotos I. Martínez-Gras J. L. Santos |
| author_sort | R. Rodriguez-Jimenez |
| collection | DOAJ |
| description |
Introduction
Negative symptoms has been classically associated with cognition, psychosocial functioning and quality of life in patients with schizophrenia. But negative symptoms are not a unitary construct, encompassing two different factors: diminished expression, and motivation and pleasure. Few works have studied the relationship between these two different negative symptoms factors and cognition (neuro and social cognition), psychosocial functioning and quality of life, jointly, in patients with a first psychotic episode of schizophrenia.
Objectives
The objective of the present work was to study, in a sample of patients with a first psychotic episode of schizophrenia, the relationship between the negative symptoms (diminished expression and motivation and pleasure) and neurocognition, social cognition, functioning and quality of life.
Methods
The study was carried out with 82 outpatients with a first psychotic episode of schizophrenia from two Spanish hospitals (“12 de Octubre” University Hospital, Madrid and “Virgen de la Luz” Hospital, Cuenca). The patients were assessed with the Clinical Assessment Interview for Negative Symptoms (CAINS) for evaluating diminished expression (EXP) and motivation and pleasure (MAP) symptoms, the MATRICS Consensus Cognitive Battery (MCCB) for evaluating neurocognition and social cognition, the Social and Occupational Functioning Assessment Scale (SOFAS), and the Quality of Life Scale (QLS).
Results
A negative correlation was found between neurocognition and the two negative symptoms subscales: CAINS-EXP (r=-0.458, p<0.001) and CAINS-MAP (r=-0.374, p<0.001); but with social cognition only CAINS-EXP was correlated (r=-0.236, p=0.033). Also, it was found a high negative correlation between SOFAS scores and CAINS-MAP (r=-0.717, p<0.001); and a medium negative correlation with CAINS-EXP (r=-0.394, p<0.001). Finally, QLS score was high correlated with both CAINS subscales: CAINS-EXP (r=-0.681, p<0.001) and CAINS-MAP (r=-0.770, p<0.001).
Conclusions
This study found a relationship between negative symptoms and neurocognition, social cognition, functioning and quality of life in a sample of patients with a first psychotic episode of schizophrenia. But the two different negative symptom factors, diminished expression, and motivation and pleasure, are associated differently with psychosocial functioning, but especially with social cognition where the relationship was only found with diminished expression symptoms.
Disclosure of Interest
None Declared |
| first_indexed | 2024-03-11T07:53:17Z |
| format | Article |
| id | doaj.art-20b041abe7344bca8e2595138cbf8532 |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:53:17Z |
| publishDate | 2023-03-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-20b041abe7344bca8e2595138cbf85322023-11-17T05:06:13ZengCambridge University PressEuropean Psychiatry0924-93381778-35852023-03-0166S641S64210.1192/j.eurpsy.2023.1334Relationship between CAINS negative symptoms and cognition, psychosocial functioning and quality of life in patients with a first psychotic episode of schizophreniaR. Rodriguez-Jimenez0L. García-Fernández1V. Romero-Ferreiro2M. Valtueña García3A. I. Aparicio4J. M. Espejo-Saavedra5L. Sánchez-Pastor6A. Nuñez-Doyle7M. Dompablo8O. Jiménez-Rodríguez9D. Rentero10P. Fernández-Sotos11I. Martínez-Gras12J. L. Santos13Psychiatry, Hospital Universitario 12 de Octubre Psychiatry, Universidad Complutense de Madrid CIBERSAM, MadridCIBERSAM, Madrid Psychiatry, Univesidad Miguel Hernandez, AlicanteCIBERSAM, Madrid Quality and Academic Compliance Unit, Universidad Europea de Madrid, MadridPsychiatry, Hospital Universitario 12 de OctubreCIBERSAM, Madrid Psychiatry, Hospital Virgen de la Luz, CuencaPsychiatry, Hospital Universitario 12 de OctubrePsychiatry, Hospital Universitario 12 de OctubrePsychiatry, Hospital Universitario 12 de OctubrePsychiatry, Hospital Universitario 12 de Octubre CIBERSAM, MadridPsychiatry, Hospital Universitario 12 de OctubrePsychiatry, Hospital Universitario 12 de OctubreCIBERSAM, Madrid Salud Mental, Complejo Hospitalario Universitario de Albacete, Albacete, SpainPsychiatry, Hospital Universitario 12 de OctubreCIBERSAM, Madrid Psychiatry, Hospital Virgen de la Luz, Cuenca Introduction Negative symptoms has been classically associated with cognition, psychosocial functioning and quality of life in patients with schizophrenia. But negative symptoms are not a unitary construct, encompassing two different factors: diminished expression, and motivation and pleasure. Few works have studied the relationship between these two different negative symptoms factors and cognition (neuro and social cognition), psychosocial functioning and quality of life, jointly, in patients with a first psychotic episode of schizophrenia. Objectives The objective of the present work was to study, in a sample of patients with a first psychotic episode of schizophrenia, the relationship between the negative symptoms (diminished expression and motivation and pleasure) and neurocognition, social cognition, functioning and quality of life. Methods The study was carried out with 82 outpatients with a first psychotic episode of schizophrenia from two Spanish hospitals (“12 de Octubre” University Hospital, Madrid and “Virgen de la Luz” Hospital, Cuenca). The patients were assessed with the Clinical Assessment Interview for Negative Symptoms (CAINS) for evaluating diminished expression (EXP) and motivation and pleasure (MAP) symptoms, the MATRICS Consensus Cognitive Battery (MCCB) for evaluating neurocognition and social cognition, the Social and Occupational Functioning Assessment Scale (SOFAS), and the Quality of Life Scale (QLS). Results A negative correlation was found between neurocognition and the two negative symptoms subscales: CAINS-EXP (r=-0.458, p<0.001) and CAINS-MAP (r=-0.374, p<0.001); but with social cognition only CAINS-EXP was correlated (r=-0.236, p=0.033). Also, it was found a high negative correlation between SOFAS scores and CAINS-MAP (r=-0.717, p<0.001); and a medium negative correlation with CAINS-EXP (r=-0.394, p<0.001). Finally, QLS score was high correlated with both CAINS subscales: CAINS-EXP (r=-0.681, p<0.001) and CAINS-MAP (r=-0.770, p<0.001). Conclusions This study found a relationship between negative symptoms and neurocognition, social cognition, functioning and quality of life in a sample of patients with a first psychotic episode of schizophrenia. But the two different negative symptom factors, diminished expression, and motivation and pleasure, are associated differently with psychosocial functioning, but especially with social cognition where the relationship was only found with diminished expression symptoms. Disclosure of Interest None Declaredhttps://www.cambridge.org/core/product/identifier/S0924933823013342/type/journal_article |
| spellingShingle | R. Rodriguez-Jimenez L. García-Fernández V. Romero-Ferreiro M. Valtueña García A. I. Aparicio J. M. Espejo-Saavedra L. Sánchez-Pastor A. Nuñez-Doyle M. Dompablo O. Jiménez-Rodríguez D. Rentero P. Fernández-Sotos I. Martínez-Gras J. L. Santos Relationship between CAINS negative symptoms and cognition, psychosocial functioning and quality of life in patients with a first psychotic episode of schizophrenia European Psychiatry |
| title | Relationship between CAINS negative symptoms and cognition, psychosocial functioning and quality of life in patients with a first psychotic episode of schizophrenia |
| title_full | Relationship between CAINS negative symptoms and cognition, psychosocial functioning and quality of life in patients with a first psychotic episode of schizophrenia |
| title_fullStr | Relationship between CAINS negative symptoms and cognition, psychosocial functioning and quality of life in patients with a first psychotic episode of schizophrenia |
| title_full_unstemmed | Relationship between CAINS negative symptoms and cognition, psychosocial functioning and quality of life in patients with a first psychotic episode of schizophrenia |
| title_short | Relationship between CAINS negative symptoms and cognition, psychosocial functioning and quality of life in patients with a first psychotic episode of schizophrenia |
| title_sort | relationship between cains negative symptoms and cognition psychosocial functioning and quality of life in patients with a first psychotic episode of schizophrenia |
| url | https://www.cambridge.org/core/product/identifier/S0924933823013342/type/journal_article |
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