Wistar rats with long-term streptozotocin-induced type 1 diabetes mellitus replicate the most relevant clinical, biochemical, and hematologic features of human diabetes / Sobolanii Wistar cu diabet zaharat tip 1 indus cu streptozotocina reproduc cele mai relevante caracteristici clinice, biochimice si hematologice ale diabetului uman
Introducere: Modelele experimentale sunt esentiale pentru elucidarea patogenezei diabetului zaharat (DZ). Ne-am propus sa realizam o descriere exhaustiva a caracteristicilor clinice, biochimice si hematologice ale sobolanilor cu DZ indus cu streptozotocina (STZ).
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2015-08-01
|
| Series: | Romanian Journal of Laboratory Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/rrlm-2015-0028 |
| _version_ | 1819117052771696640 |
|---|---|
| author | Scridon Alina Perian Marcel Marginean Alina Fisca Ciprian Vantu Adriana Ghertescu Doina Chevalier Philippe Serban Razvan Constantin |
| author_facet | Scridon Alina Perian Marcel Marginean Alina Fisca Ciprian Vantu Adriana Ghertescu Doina Chevalier Philippe Serban Razvan Constantin |
| author_sort | Scridon Alina |
| collection | DOAJ |
| description | Introducere: Modelele experimentale sunt esentiale pentru elucidarea patogenezei diabetului zaharat (DZ). Ne-am propus sa realizam o descriere exhaustiva a caracteristicilor clinice, biochimice si hematologice ale sobolanilor cu DZ indus cu streptozotocina (STZ). |
| first_indexed | 2024-12-22T05:26:51Z |
| format | Article |
| id | doaj.art-20b0f43b0f6e47ac8eea3b0d16a4d768 |
| institution | Directory Open Access Journal |
| issn | 2284-5623 |
| language | English |
| last_indexed | 2024-12-22T05:26:51Z |
| publishDate | 2015-08-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Romanian Journal of Laboratory Medicine |
| spelling | doaj.art-20b0f43b0f6e47ac8eea3b0d16a4d7682022-12-21T18:37:34ZengSciendoRomanian Journal of Laboratory Medicine2284-56232015-08-0123326327410.1515/rrlm-2015-0028rrlm-2015-0028Wistar rats with long-term streptozotocin-induced type 1 diabetes mellitus replicate the most relevant clinical, biochemical, and hematologic features of human diabetes / Sobolanii Wistar cu diabet zaharat tip 1 indus cu streptozotocina reproduc cele mai relevante caracteristici clinice, biochimice si hematologice ale diabetului umanScridon Alina0Perian Marcel1Marginean Alina2Fisca Ciprian3Vantu Adriana4Ghertescu Doina5Chevalier Philippe6Serban Razvan Constantin7University of Medicine and Pharmacy of Tirgu Mures, RomaniaUniversity of Medicine and Pharmacy of Tirgu Mures, RomaniaUniversity of Medicine and Pharmacy of Tirgu Mures, RomaniaUniversity of Medicine and Pharmacy of Tirgu Mures, RomaniaUniversity of Medicine and Pharmacy of Tirgu Mures, RomaniaUniversity of Medicine and Pharmacy of Tirgu Mures, RomaniaService de Rythmologie, Hospices Civils de Lyon, Hopital Louis Pradel, Bron Cedex 69500, FranceEmergency Institute for Cardiovascular Diseases and Transplantation Tirgu Mures, RomaniaIntroducere: Modelele experimentale sunt esentiale pentru elucidarea patogenezei diabetului zaharat (DZ). Ne-am propus sa realizam o descriere exhaustiva a caracteristicilor clinice, biochimice si hematologice ale sobolanilor cu DZ indus cu streptozotocina (STZ).https://doi.org/10.1515/rrlm-2015-0028experimental modelwistar ratslong-term follow-upstreptozotocintype 1 diabetes mellitusmodel experimentalsobolani wistarurmarire pe termen lungstreptozotocinadiabet zaharat tip 1 |
| spellingShingle | Scridon Alina Perian Marcel Marginean Alina Fisca Ciprian Vantu Adriana Ghertescu Doina Chevalier Philippe Serban Razvan Constantin Wistar rats with long-term streptozotocin-induced type 1 diabetes mellitus replicate the most relevant clinical, biochemical, and hematologic features of human diabetes / Sobolanii Wistar cu diabet zaharat tip 1 indus cu streptozotocina reproduc cele mai relevante caracteristici clinice, biochimice si hematologice ale diabetului uman Romanian Journal of Laboratory Medicine experimental model wistar rats long-term follow-up streptozotocin type 1 diabetes mellitus model experimental sobolani wistar urmarire pe termen lung streptozotocina diabet zaharat tip 1 |
| title | Wistar rats with long-term streptozotocin-induced type 1 diabetes mellitus replicate the most relevant clinical, biochemical, and hematologic features of human diabetes / Sobolanii Wistar cu diabet zaharat tip 1 indus cu streptozotocina reproduc cele mai relevante caracteristici clinice, biochimice si hematologice ale diabetului uman |
| title_full | Wistar rats with long-term streptozotocin-induced type 1 diabetes mellitus replicate the most relevant clinical, biochemical, and hematologic features of human diabetes / Sobolanii Wistar cu diabet zaharat tip 1 indus cu streptozotocina reproduc cele mai relevante caracteristici clinice, biochimice si hematologice ale diabetului uman |
| title_fullStr | Wistar rats with long-term streptozotocin-induced type 1 diabetes mellitus replicate the most relevant clinical, biochemical, and hematologic features of human diabetes / Sobolanii Wistar cu diabet zaharat tip 1 indus cu streptozotocina reproduc cele mai relevante caracteristici clinice, biochimice si hematologice ale diabetului uman |
| title_full_unstemmed | Wistar rats with long-term streptozotocin-induced type 1 diabetes mellitus replicate the most relevant clinical, biochemical, and hematologic features of human diabetes / Sobolanii Wistar cu diabet zaharat tip 1 indus cu streptozotocina reproduc cele mai relevante caracteristici clinice, biochimice si hematologice ale diabetului uman |
| title_short | Wistar rats with long-term streptozotocin-induced type 1 diabetes mellitus replicate the most relevant clinical, biochemical, and hematologic features of human diabetes / Sobolanii Wistar cu diabet zaharat tip 1 indus cu streptozotocina reproduc cele mai relevante caracteristici clinice, biochimice si hematologice ale diabetului uman |
| title_sort | wistar rats with long term streptozotocin induced type 1 diabetes mellitus replicate the most relevant clinical biochemical and hematologic features of human diabetes sobolanii wistar cu diabet zaharat tip 1 indus cu streptozotocina reproduc cele mai relevante caracteristici clinice biochimice si hematologice ale diabetului uman |
| topic | experimental model wistar rats long-term follow-up streptozotocin type 1 diabetes mellitus model experimental sobolani wistar urmarire pe termen lung streptozotocina diabet zaharat tip 1 |
| url | https://doi.org/10.1515/rrlm-2015-0028 |
| work_keys_str_mv | AT scridonalina wistarratswithlongtermstreptozotocininducedtype1diabetesmellitusreplicatethemostrelevantclinicalbiochemicalandhematologicfeaturesofhumandiabetessobolaniiwistarcudiabetzaharattip1induscustreptozotocinareproduccelemairelevantecaracteristiciclinicebiochimice AT perianmarcel wistarratswithlongtermstreptozotocininducedtype1diabetesmellitusreplicatethemostrelevantclinicalbiochemicalandhematologicfeaturesofhumandiabetessobolaniiwistarcudiabetzaharattip1induscustreptozotocinareproduccelemairelevantecaracteristiciclinicebiochimice AT margineanalina wistarratswithlongtermstreptozotocininducedtype1diabetesmellitusreplicatethemostrelevantclinicalbiochemicalandhematologicfeaturesofhumandiabetessobolaniiwistarcudiabetzaharattip1induscustreptozotocinareproduccelemairelevantecaracteristiciclinicebiochimice AT fiscaciprian wistarratswithlongtermstreptozotocininducedtype1diabetesmellitusreplicatethemostrelevantclinicalbiochemicalandhematologicfeaturesofhumandiabetessobolaniiwistarcudiabetzaharattip1induscustreptozotocinareproduccelemairelevantecaracteristiciclinicebiochimice AT vantuadriana wistarratswithlongtermstreptozotocininducedtype1diabetesmellitusreplicatethemostrelevantclinicalbiochemicalandhematologicfeaturesofhumandiabetessobolaniiwistarcudiabetzaharattip1induscustreptozotocinareproduccelemairelevantecaracteristiciclinicebiochimice AT ghertescudoina wistarratswithlongtermstreptozotocininducedtype1diabetesmellitusreplicatethemostrelevantclinicalbiochemicalandhematologicfeaturesofhumandiabetessobolaniiwistarcudiabetzaharattip1induscustreptozotocinareproduccelemairelevantecaracteristiciclinicebiochimice AT chevalierphilippe wistarratswithlongtermstreptozotocininducedtype1diabetesmellitusreplicatethemostrelevantclinicalbiochemicalandhematologicfeaturesofhumandiabetessobolaniiwistarcudiabetzaharattip1induscustreptozotocinareproduccelemairelevantecaracteristiciclinicebiochimice AT serbanrazvanconstantin wistarratswithlongtermstreptozotocininducedtype1diabetesmellitusreplicatethemostrelevantclinicalbiochemicalandhematologicfeaturesofhumandiabetessobolaniiwistarcudiabetzaharattip1induscustreptozotocinareproduccelemairelevantecaracteristiciclinicebiochimice |