Role of fine-needle aspiration cytology in the evaluation of salivary gland lesion with utilization of Milan system for reporting
Background: Fine-needle aspiration cytology (FNAC) plays a role in the pre-operative diagnosis of salivary gland mass lesion. Salivary gland neoplasm accounts for 6% of all head and neck tumors. It is widely used safe and relatively non-traumatic procedure that can quickly provide important informat...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2024-01-01
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| Series: | Asian Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/57363 |
| _version_ | 1797368214087270400 |
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| author | Alka Ambedkar Rashmi Nayak Mangeet Dhurve Kavita Sachdewa Jagmohan Singh Dhakar |
| author_facet | Alka Ambedkar Rashmi Nayak Mangeet Dhurve Kavita Sachdewa Jagmohan Singh Dhakar |
| author_sort | Alka Ambedkar |
| collection | DOAJ |
| description | Background: Fine-needle aspiration cytology (FNAC) plays a role in the pre-operative diagnosis of salivary gland mass lesion. Salivary gland neoplasm accounts for 6% of all head and neck tumors. It is widely used safe and relatively non-traumatic procedure that can quickly provide important information. “The Milan system for reporting salivary gland cytopathology” (MSRSGC) was introduced, providing a guide for diagnosis and management according to the risk of malignancy (ROM) in different categories.
Aims and Objectives: The objectives of the study are as follows: (1) To evaluate different types of salivary gland lesion in tertiary care center. (2) To see application of Milan system in the present scenario.
Materials and Methods: A hospital-based and prospective study was conducted between March 2021 and September 2022 on all cases of salivary gland lesions who were referred for FNAC to the Department of Pathology at Netaji Subhash Chandra Bose Medical College Hospital in Jabalpur, Madhya Pradesh. In the present study, we categorize salivary gland cytopathology result as per Milan system (MSRSGC) and calculated diagnostic accuracy and ROM in each category of Milan system (MSRSGC).
Results: Seventy seven cases distributed according to Milan category as follows: Non-diagnostic (ND) (2.59), non-neoplastic (NN) (29.33%), atypia of undetermined significance (AUS) (1.29%), 4a. Benign (29.87%), 4b. Salivary gland neoplasm of uncertain malignant potential (SUMP) (1.29%), suspicious of malignancy (SOM) (1.29%), and malignancy (10.38%). Out of 77 cases, histological follow-up was available in 27 cases and the ROM was calculated. The ROM for each category of the Milan system is as follows: ND (0%), NN (6.66%), AUS (100%), 4a. Benign (9.09%), 4b. SUMP (0%), SOM (100%), and Malignancy (100%). The sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy were 77.7%, 100%, 100%, 92.59%, and 94.11%.
Conclusion: FNAC of the salivary gland lesions is a safe, minimum invasive, and reliable diagnostic procedure. The Milan system of reporting is a risk stratification system which can improve the overall effectiveness of reporting. |
| first_indexed | 2024-03-08T17:29:26Z |
| format | Article |
| id | doaj.art-20b23e8b9f2e461c8575573a2b74aa77 |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-03-08T17:29:26Z |
| publishDate | 2024-01-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-20b23e8b9f2e461c8575573a2b74aa772024-01-02T16:15:55ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762024-01-01151181188https://doi.org/10.3126/ajms.v15i1.57363Role of fine-needle aspiration cytology in the evaluation of salivary gland lesion with utilization of Milan system for reportingAlka Ambedkar 0https://orcid.org/0009-0000-3091-6982Rashmi Nayak 1https://orcid.org/0009-0008-0336-0200Mangeet Dhurve 2https://orcid.org/0009-0005-9071-4916Kavita Sachdewa 3Jagmohan Singh Dhakar 4https://orcid.org/0000-0001-9592-3227Postgraduate Resident, Department of Pathology, Netaji Subhash Chandra Bose Medical College, Jabalpur, Madhya Pradesh, India Associate Professor, Department of Pathology, Netaji Subhash Chandra Bose Medical College, Jabalpur, Madhya Pradesh, India Demonstrator, Department of Pathology, Netaji Subhash Chandra Bose Medical College, Jabalpur, Madhya Pradesh, India Professor and Head, Department of ENT, Netaji Subhash Chandra Bose Medical College, Jabalpur, Madhya Pradesh, IndiaStatistician, Department of Community Medicine, Netaji Subhash Chandra Bose Medical College, Jabalpur, Madhya Pradesh, India Background: Fine-needle aspiration cytology (FNAC) plays a role in the pre-operative diagnosis of salivary gland mass lesion. Salivary gland neoplasm accounts for 6% of all head and neck tumors. It is widely used safe and relatively non-traumatic procedure that can quickly provide important information. “The Milan system for reporting salivary gland cytopathology” (MSRSGC) was introduced, providing a guide for diagnosis and management according to the risk of malignancy (ROM) in different categories. Aims and Objectives: The objectives of the study are as follows: (1) To evaluate different types of salivary gland lesion in tertiary care center. (2) To see application of Milan system in the present scenario. Materials and Methods: A hospital-based and prospective study was conducted between March 2021 and September 2022 on all cases of salivary gland lesions who were referred for FNAC to the Department of Pathology at Netaji Subhash Chandra Bose Medical College Hospital in Jabalpur, Madhya Pradesh. In the present study, we categorize salivary gland cytopathology result as per Milan system (MSRSGC) and calculated diagnostic accuracy and ROM in each category of Milan system (MSRSGC). Results: Seventy seven cases distributed according to Milan category as follows: Non-diagnostic (ND) (2.59), non-neoplastic (NN) (29.33%), atypia of undetermined significance (AUS) (1.29%), 4a. Benign (29.87%), 4b. Salivary gland neoplasm of uncertain malignant potential (SUMP) (1.29%), suspicious of malignancy (SOM) (1.29%), and malignancy (10.38%). Out of 77 cases, histological follow-up was available in 27 cases and the ROM was calculated. The ROM for each category of the Milan system is as follows: ND (0%), NN (6.66%), AUS (100%), 4a. Benign (9.09%), 4b. SUMP (0%), SOM (100%), and Malignancy (100%). The sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy were 77.7%, 100%, 100%, 92.59%, and 94.11%. Conclusion: FNAC of the salivary gland lesions is a safe, minimum invasive, and reliable diagnostic procedure. The Milan system of reporting is a risk stratification system which can improve the overall effectiveness of reporting.https://www.nepjol.info/index.php/AJMS/article/view/57363fine-needle aspiration cytology; milan system for reporting salivary gland cytopathology; salivary gland lesion |
| spellingShingle | Alka Ambedkar Rashmi Nayak Mangeet Dhurve Kavita Sachdewa Jagmohan Singh Dhakar Role of fine-needle aspiration cytology in the evaluation of salivary gland lesion with utilization of Milan system for reporting Asian Journal of Medical Sciences fine-needle aspiration cytology; milan system for reporting salivary gland cytopathology; salivary gland lesion |
| title | Role of fine-needle aspiration cytology in the evaluation of salivary gland lesion with utilization of Milan system for reporting |
| title_full | Role of fine-needle aspiration cytology in the evaluation of salivary gland lesion with utilization of Milan system for reporting |
| title_fullStr | Role of fine-needle aspiration cytology in the evaluation of salivary gland lesion with utilization of Milan system for reporting |
| title_full_unstemmed | Role of fine-needle aspiration cytology in the evaluation of salivary gland lesion with utilization of Milan system for reporting |
| title_short | Role of fine-needle aspiration cytology in the evaluation of salivary gland lesion with utilization of Milan system for reporting |
| title_sort | role of fine needle aspiration cytology in the evaluation of salivary gland lesion with utilization of milan system for reporting |
| topic | fine-needle aspiration cytology; milan system for reporting salivary gland cytopathology; salivary gland lesion |
| url | https://www.nepjol.info/index.php/AJMS/article/view/57363 |
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