Expression of FIBCD1 by intestinal epithelial cells alleviates inflammation-driven tumorigenesis in a mouse model of colorectal cancer

Expression of FIBCD1 by intestinal epithelial cells alleviates inflammation-driven tumorigenesis in a mouse model of colorectal cancer

BackgroundColorectal cancer (CRC) ranks as the third most prevalent cancer globally, highlighting the pressing need to address its development. Inflammation plays a crucial role in augmenting the risk of CRC and actively contributes to all stages of tumorigenesis. Consequently, targeting early infla...

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Bibliographic Details
Main Authors: Vahid Khaze Shahgoli, Magdalena Dubik, Bartosz Pilecki, Sofie Skallerup, Sandra Gaedt Schmidt, Sönke Detlefsen, Grith L. Sorensen, Uffe Holmskov, Behzad Baradaran, Jesper B. Moeller
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Oncology
Subjects:
Fibcd1
intestinal epithelial cells
AOM/DSS
CRC
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1280891/full

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