T908 Polymeric Micelles Improved the Uptake of Sgc8-c Aptamer Probe in Tumor-Bearing Mice: A Co-Association Study between the Probe and Preformed Nanostructures

T908 Polymeric Micelles Improved the Uptake of Sgc8-c Aptamer Probe in Tumor-Bearing Mice: A Co-Association Study between the Probe and Preformed Nanostructures

Aptamers are oligonucleotides that have the characteristic of recognizing a target with high affinity and specificity. Based on our previous studies, the aptamer probe Sgc8-c-Alexa647 is a promising tool for molecular imaging of PTK7, which is an interesting biomarker in cancer. In order to improve...

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Bibliographic Details
Main Authors: Romina Castelli, Manuel Ibarra, Ricardo Faccio, Iris Miraballes, Marcelo Fernández, Albertina Moglioni, Pablo Cabral, Hugo Cerecetto, Romina J. Glisoni, Victoria Calzada
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceuticals
Subjects:
Sgc8-c aptamer
probe
polymeric micelles
liposomes
active targeting
Online Access:https://www.mdpi.com/1424-8247/15/1/15

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