Cancer associated fibroblasts-derived SULF1 promotes gastric cancer metastasis and CDDP resistance through the TGFBR3-mediated TGF-β signaling pathway

Abstract SULF1 has been implicated in a number of malignancies. The function of SULF1 in gastric cancer is disputed. The objective of this study was to examine the role and underlying molecular mechanisms of SULF1 in the context of gastric cancer. We found that the expression of SULF1 was increased...

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Bibliographic Details
Main Authors: Xingchao Fang, Damin Chen, Xinyu Yang, Xiaogang Cao, Quan Cheng, Kanghui Liu, Peng Xu, Yanjuan Wang, Jiafeng Xu, Siguo Zhao, Zhengyuan Yan
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01882-y

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