Disruption of STAT5A and NMI signaling axis leads to ISG20-driven metastatic mammary tumors

Disruption of STAT5A and NMI signaling axis leads to ISG20-driven metastatic mammary tumors

Abstract Molecular dynamics of developmental processes are repurposed by cancer cells to support cancer initiation and progression. Disruption of the delicate balance between cellular differentiation and plasticity during mammary development leads to breast cancer initiation and metastatic progressi...

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Bibliographic Details
Main Authors: Heba Allah M. Alsheikh, Brandon J. Metge, Hawley C. Pruitt, Sarah C. Kammerud, Dongquan Chen, Shi Wei, Lalita A. Shevde, Rajeev S. Samant
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-021-00333-y

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