Reversible renal impairment induced by treatment with the angiotensin II receptor antagonist candesartan in a patient with bilateral renal artery stenosis

<p>Abstract</p> <p>Background</p> <p>It is well established that ACE-inhibitors should be avoided in patients with renal artery stenosis. In recent years it has also been recommended that caution should be demonstrated when angiotensin II blockers are used in the same t...

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Main Authors: Kjaer Andreas, Johansen Thomas
Format: Article
Language:English
Published: BMC 2001-05-01
Series:BMC Nephrology
Online Access:http://www.biomedcentral.com/1471-2369/2/1
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author Kjaer Andreas
Johansen Thomas
author_facet Kjaer Andreas
Johansen Thomas
author_sort Kjaer Andreas
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>It is well established that ACE-inhibitors should be avoided in patients with renal artery stenosis. In recent years it has also been recommended that caution should be demonstrated when angiotensin II blockers are used in the same type of patients but the evidence is based only on few cases.</p> <p>Results</p> <p>We describe a case where use of the angiotensin II antagonist candesartan (Atacand) induced renal failure in a patient with bilateral renal artery stenosis. The course of the case is enlighted by results from sequential renography, selective renal vein catheterisation for measurement of renin, and angiographic findings.</p> <p>Conclusions</p> <p>In patients with renal artery stenosis the angiotensin II antagonist candesartan should be avoided.</p>
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spelling doaj.art-20b992eb363d4f53b2cdef7c7b819e412022-12-21T22:10:44ZengBMCBMC Nephrology1471-23692001-05-0121110.1186/1471-2369-2-1Reversible renal impairment induced by treatment with the angiotensin II receptor antagonist candesartan in a patient with bilateral renal artery stenosisKjaer AndreasJohansen Thomas<p>Abstract</p> <p>Background</p> <p>It is well established that ACE-inhibitors should be avoided in patients with renal artery stenosis. In recent years it has also been recommended that caution should be demonstrated when angiotensin II blockers are used in the same type of patients but the evidence is based only on few cases.</p> <p>Results</p> <p>We describe a case where use of the angiotensin II antagonist candesartan (Atacand) induced renal failure in a patient with bilateral renal artery stenosis. The course of the case is enlighted by results from sequential renography, selective renal vein catheterisation for measurement of renin, and angiographic findings.</p> <p>Conclusions</p> <p>In patients with renal artery stenosis the angiotensin II antagonist candesartan should be avoided.</p>http://www.biomedcentral.com/1471-2369/2/1
spellingShingle Kjaer Andreas
Johansen Thomas
Reversible renal impairment induced by treatment with the angiotensin II receptor antagonist candesartan in a patient with bilateral renal artery stenosis
BMC Nephrology
title Reversible renal impairment induced by treatment with the angiotensin II receptor antagonist candesartan in a patient with bilateral renal artery stenosis
title_full Reversible renal impairment induced by treatment with the angiotensin II receptor antagonist candesartan in a patient with bilateral renal artery stenosis
title_fullStr Reversible renal impairment induced by treatment with the angiotensin II receptor antagonist candesartan in a patient with bilateral renal artery stenosis
title_full_unstemmed Reversible renal impairment induced by treatment with the angiotensin II receptor antagonist candesartan in a patient with bilateral renal artery stenosis
title_short Reversible renal impairment induced by treatment with the angiotensin II receptor antagonist candesartan in a patient with bilateral renal artery stenosis
title_sort reversible renal impairment induced by treatment with the angiotensin ii receptor antagonist candesartan in a patient with bilateral renal artery stenosis
url http://www.biomedcentral.com/1471-2369/2/1
work_keys_str_mv AT kjaerandreas reversiblerenalimpairmentinducedbytreatmentwiththeangiotensiniireceptorantagonistcandesartaninapatientwithbilateralrenalarterystenosis
AT johansenthomas reversiblerenalimpairmentinducedbytreatmentwiththeangiotensiniireceptorantagonistcandesartaninapatientwithbilateralrenalarterystenosis