Simultaneous Bilateral Testicular Metastases from Renal Clear Cell Carcinoma: A Rare Presentation in Von Hippel–Lindau disease
In this article, we present a Von Hippel–Lindau (VHL) patient with synchoronus bilateral testicular metastasis from renal cell carcinoma (RCC). A 50 year-old man, a known case of VHL syndrome was referred with palpable masses in both the testes. His medical history demonstrated that he had undergon...
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| Format: | Article |
| Language: | English |
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Codon Publications
2022-05-01
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| Series: | Journal of Kidney Cancer and VHL |
| Subjects: | |
| Online Access: | https://www.jkcvhl.com/index.php/jkcvhl/article/view/211 |
| _version_ | 1828107506206900224 |
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| author | Asaad Moradi Delaram Farhoumand Behnaz Bouzari Behnam Shakiba |
| author_facet | Asaad Moradi Delaram Farhoumand Behnaz Bouzari Behnam Shakiba |
| author_sort | Asaad Moradi |
| collection | DOAJ |
| description |
In this article, we present a Von Hippel–Lindau (VHL) patient with synchoronus bilateral testicular metastasis from renal cell carcinoma (RCC). A 50 year-old man, a known case of VHL syndrome was referred with palpable masses in both the testes. His medical history demonstrated that he had undergone the brain surgery for cerebellar hemangioblastoma. He had undergone simultaneous Whipple’s pancreatectomy and left radical nephrectomy becuase of well-differentiated neuroendocrine tumors in head and body of the pancreas and a 6-cm clear cell-type grade-3 RCC in the left kidney. Scrotal sonography demonstrated vascular and heteroechogen masses measuring 19×14 mm in lower pole of the right testicle, 19×16 mm in upper pole of the right testicle, and 23×16.5 mm in upper pole of the left testicle. After having patient’s consent, bilateral orchiectomy was performed by inguinal incision. Histopathologic examination and immunohistochemistry staining revealed metastasis from RCC. The most common neoplasm of reproductive system in VHL patients is epididymal papillary cystadenoma. Owing to it’s benign nature, the management is conservative with routine physical examination and ultrasonography. Our patient indicated that every scrotal mass in patients with VHL is not to be considered as epididymal papillary cystadenoma.
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| first_indexed | 2024-04-11T10:33:21Z |
| format | Article |
| id | doaj.art-20bcc8f9ab264f9cb6e995eb069116cb |
| institution | Directory Open Access Journal |
| issn | 2203-5826 |
| language | English |
| last_indexed | 2024-04-11T10:33:21Z |
| publishDate | 2022-05-01 |
| publisher | Codon Publications |
| record_format | Article |
| series | Journal of Kidney Cancer and VHL |
| spelling | doaj.art-20bcc8f9ab264f9cb6e995eb069116cb2022-12-22T04:29:23ZengCodon PublicationsJournal of Kidney Cancer and VHL2203-58262022-05-019210.15586/jkcvhl.v9i2.211Simultaneous Bilateral Testicular Metastases from Renal Clear Cell Carcinoma: A Rare Presentation in Von Hippel–Lindau diseaseAsaad Moradi0Delaram Farhoumand1Behnaz Bouzari2Behnam Shakiba3Department of Urology, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.Department of Urology, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.Department of Pathology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.Department of Urology, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. In this article, we present a Von Hippel–Lindau (VHL) patient with synchoronus bilateral testicular metastasis from renal cell carcinoma (RCC). A 50 year-old man, a known case of VHL syndrome was referred with palpable masses in both the testes. His medical history demonstrated that he had undergone the brain surgery for cerebellar hemangioblastoma. He had undergone simultaneous Whipple’s pancreatectomy and left radical nephrectomy becuase of well-differentiated neuroendocrine tumors in head and body of the pancreas and a 6-cm clear cell-type grade-3 RCC in the left kidney. Scrotal sonography demonstrated vascular and heteroechogen masses measuring 19×14 mm in lower pole of the right testicle, 19×16 mm in upper pole of the right testicle, and 23×16.5 mm in upper pole of the left testicle. After having patient’s consent, bilateral orchiectomy was performed by inguinal incision. Histopathologic examination and immunohistochemistry staining revealed metastasis from RCC. The most common neoplasm of reproductive system in VHL patients is epididymal papillary cystadenoma. Owing to it’s benign nature, the management is conservative with routine physical examination and ultrasonography. Our patient indicated that every scrotal mass in patients with VHL is not to be considered as epididymal papillary cystadenoma. https://www.jkcvhl.com/index.php/jkcvhl/article/view/211neoplasm metastasisrenal cell carcinomavon hippel lindau diseasetestis |
| spellingShingle | Asaad Moradi Delaram Farhoumand Behnaz Bouzari Behnam Shakiba Simultaneous Bilateral Testicular Metastases from Renal Clear Cell Carcinoma: A Rare Presentation in Von Hippel–Lindau disease Journal of Kidney Cancer and VHL neoplasm metastasis renal cell carcinoma von hippel lindau disease testis |
| title | Simultaneous Bilateral Testicular Metastases from Renal Clear Cell Carcinoma: A Rare Presentation in Von Hippel–Lindau disease |
| title_full | Simultaneous Bilateral Testicular Metastases from Renal Clear Cell Carcinoma: A Rare Presentation in Von Hippel–Lindau disease |
| title_fullStr | Simultaneous Bilateral Testicular Metastases from Renal Clear Cell Carcinoma: A Rare Presentation in Von Hippel–Lindau disease |
| title_full_unstemmed | Simultaneous Bilateral Testicular Metastases from Renal Clear Cell Carcinoma: A Rare Presentation in Von Hippel–Lindau disease |
| title_short | Simultaneous Bilateral Testicular Metastases from Renal Clear Cell Carcinoma: A Rare Presentation in Von Hippel–Lindau disease |
| title_sort | simultaneous bilateral testicular metastases from renal clear cell carcinoma a rare presentation in von hippel lindau disease |
| topic | neoplasm metastasis renal cell carcinoma von hippel lindau disease testis |
| url | https://www.jkcvhl.com/index.php/jkcvhl/article/view/211 |
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