Design of a self-driven probiotic-CRISPR/Cas9 nanosystem for sono-immunometabolic cancer therapy
Recently, strategies based on the integration of nanotechnology with microbial carriers have been proposed for cancer therapy. Here the authors report the design of an ultrasound-controlled CRISPR/Cas9 gene editing system for IDO1 silencing compounded with the probiotic Lactobacillus rhamnosus GG, s...
Main Authors: | Jifeng Yu, Bangguo Zhou, Shen Zhang, Haohao Yin, Liping Sun, Yinying Pu, Boyang Zhou, Yikang Sun, Xiaolong Li, Yan Fang, Lifan Wang, Chongke Zhao, Dou Du, Yan Zhang, Huixiong Xu |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-12-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-35580-z |
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