Differences in the prevalence of vitamin D deficiency and hip fractures in nursing home residents and independently living elderly
ABSTRACT Objective To compare the prevalence of vitamin D deficiency and fracture history in nursing home residents and community-dwelling elderly subjects and to explore the association of vitamin D levels with various characteristics. Materials and methods Sixty-six nursing home residents and 13...
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| Format: | Article |
| Language: | English |
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Brazilian Society of Endocrinology and Metabolism
2016-02-01
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| Series: | Archives of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972016000300217&lng=en&tlng=en |
| _version_ | 1818558049357398016 |
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| author | Alexander Shinkov Anna-Maria Borissova Lilia Dakovska Jordan Vlahov Lidia Kassabova Dobrin Svinarov Stefan Krivoshiev |
| author_facet | Alexander Shinkov Anna-Maria Borissova Lilia Dakovska Jordan Vlahov Lidia Kassabova Dobrin Svinarov Stefan Krivoshiev |
| author_sort | Alexander Shinkov |
| collection | DOAJ |
| description | ABSTRACT Objective To compare the prevalence of vitamin D deficiency and fracture history in nursing home residents and community-dwelling elderly subjects and to explore the association of vitamin D levels with various characteristics. Materials and methods Sixty-six nursing home residents and 139 community-dwelling elderly subjects participated. Marital status, medical history, medication including vitamin D supplements, smoking, past fractures were assessed. Weight and height were measured and body mass index calculated. Serum 25-hydroxyvitamin D (25-OHD), PTH, Ca, phosphate, creatinine and eGFR were determined. Results In the nursing home residents 25-OHD was lower (17.8 nmol/l, [9.4-28.6] vs. 36.7 nmol/l, [26.9-50], p < 0.001), PTH was higher (5.6 pmol/l, [3.9-8.9] vs. 4.7 pmol/l [3.6-5.8], P = 0.003) and 25-OHD deficiency was more prevalent (65.2% [53.7-76.7] vs. 22.3% [15.4-29.2], p < 0.001) as was elevated PTH (23% [12.8-33] vs. 5.8% [2-10], p = 0.001). 25-OHD correlated negatively with PTH (institutionalized r = -0.28, p = 0.025 and community-dwelling r = -0.36, p < 0.001). Hip fractures were reported by 8% of the residents and 2% of the independent elderly. The only predictor for hip fracture was elevated PTH (OR = 7.6 (1.5-36.9), p = 0.013). Conclusion The prevalence of vitamin D deficiency and secondary hyperparathyroidism was high in the institutionalized subjects. Hip fracture risk was associated with elevated PTH and not directly with vitamin D levels or the residency status. |
| first_indexed | 2024-12-14T00:07:42Z |
| format | Article |
| id | doaj.art-20c331a23337460b9bf60d0ded6722a2 |
| institution | Directory Open Access Journal |
| issn | 2359-4292 |
| language | English |
| last_indexed | 2024-12-14T00:07:42Z |
| publishDate | 2016-02-01 |
| publisher | Brazilian Society of Endocrinology and Metabolism |
| record_format | Article |
| series | Archives of Endocrinology and Metabolism |
| spelling | doaj.art-20c331a23337460b9bf60d0ded6722a22022-12-21T23:25:54ZengBrazilian Society of Endocrinology and MetabolismArchives of Endocrinology and Metabolism2359-42922016-02-0160321722210.1590/2359-3997000000109S2359-39972016000300217Differences in the prevalence of vitamin D deficiency and hip fractures in nursing home residents and independently living elderlyAlexander ShinkovAnna-Maria BorissovaLilia DakovskaJordan VlahovLidia KassabovaDobrin SvinarovStefan KrivoshievABSTRACT Objective To compare the prevalence of vitamin D deficiency and fracture history in nursing home residents and community-dwelling elderly subjects and to explore the association of vitamin D levels with various characteristics. Materials and methods Sixty-six nursing home residents and 139 community-dwelling elderly subjects participated. Marital status, medical history, medication including vitamin D supplements, smoking, past fractures were assessed. Weight and height were measured and body mass index calculated. Serum 25-hydroxyvitamin D (25-OHD), PTH, Ca, phosphate, creatinine and eGFR were determined. Results In the nursing home residents 25-OHD was lower (17.8 nmol/l, [9.4-28.6] vs. 36.7 nmol/l, [26.9-50], p < 0.001), PTH was higher (5.6 pmol/l, [3.9-8.9] vs. 4.7 pmol/l [3.6-5.8], P = 0.003) and 25-OHD deficiency was more prevalent (65.2% [53.7-76.7] vs. 22.3% [15.4-29.2], p < 0.001) as was elevated PTH (23% [12.8-33] vs. 5.8% [2-10], p = 0.001). 25-OHD correlated negatively with PTH (institutionalized r = -0.28, p = 0.025 and community-dwelling r = -0.36, p < 0.001). Hip fractures were reported by 8% of the residents and 2% of the independent elderly. The only predictor for hip fracture was elevated PTH (OR = 7.6 (1.5-36.9), p = 0.013). Conclusion The prevalence of vitamin D deficiency and secondary hyperparathyroidism was high in the institutionalized subjects. Hip fracture risk was associated with elevated PTH and not directly with vitamin D levels or the residency status.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972016000300217&lng=en&tlng=en25-hydroxyvitamin Dvitamin D deficiencyvitamin D insufficiencyelderlynursing home residents |
| spellingShingle | Alexander Shinkov Anna-Maria Borissova Lilia Dakovska Jordan Vlahov Lidia Kassabova Dobrin Svinarov Stefan Krivoshiev Differences in the prevalence of vitamin D deficiency and hip fractures in nursing home residents and independently living elderly Archives of Endocrinology and Metabolism 25-hydroxyvitamin D vitamin D deficiency vitamin D insufficiency elderly nursing home residents |
| title | Differences in the prevalence of vitamin D deficiency and hip fractures in nursing home residents and independently living elderly |
| title_full | Differences in the prevalence of vitamin D deficiency and hip fractures in nursing home residents and independently living elderly |
| title_fullStr | Differences in the prevalence of vitamin D deficiency and hip fractures in nursing home residents and independently living elderly |
| title_full_unstemmed | Differences in the prevalence of vitamin D deficiency and hip fractures in nursing home residents and independently living elderly |
| title_short | Differences in the prevalence of vitamin D deficiency and hip fractures in nursing home residents and independently living elderly |
| title_sort | differences in the prevalence of vitamin d deficiency and hip fractures in nursing home residents and independently living elderly |
| topic | 25-hydroxyvitamin D vitamin D deficiency vitamin D insufficiency elderly nursing home residents |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972016000300217&lng=en&tlng=en |
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