Pathophysiological Correlation between Diabetes Mellitus Type-II and Chronic Obstructive Pulmonary Diseases
INTRODUCTION: Diabetes Mellitus, a chronic disease is usually associated and linked to many other conditions and complications. Chronic Obstructive Pulmonary Disease (COPD); a life threatening progressive inflammatory lung disease associated with chronic bronchitis and emphysema; when associated wit...
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| Format: | Article |
| Language: | English |
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Liaquat University of Medical and Health Sciences
2017-03-01
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| Series: | JLUMHS |
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| Online Access: | https://www.lumhs.edu.pk/jlumhs/Vol16No01/pdfs/09.pdf |
| _version_ | 1797810902051848192 |
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| author | Ahmad N. Bitar Muhammad Ali Ghoto Abdullah Dayo Mudassar Iqbal Arain Rabia Parveen |
| author_facet | Ahmad N. Bitar Muhammad Ali Ghoto Abdullah Dayo Mudassar Iqbal Arain Rabia Parveen |
| author_sort | Ahmad N. Bitar |
| collection | DOAJ |
| description | INTRODUCTION: Diabetes Mellitus, a chronic disease is usually associated and linked to many other conditions and complications. Chronic Obstructive Pulmonary Disease (COPD); a life threatening progressive inflammatory lung disease associated with chronic bronchitis and emphysema; when associated with Diabetes Mellitus generates a huge burden on patients quality of life as well as on health care systems.
OBJECTIVE: Although link between DM and COPD is not scientifically established or confirmed yet, however evidence suggest a pathophysiological correlation between both conditions might be present.
This study focuses upon impact of DM on the onset of COPD and to find if there is any evidence of the suggested pathophysiological correlation.
METHODOLOGY: We retrospectively analyzed 120 cases of Chronic Obstructive Pulmonary Disease (COPD), data collected from General Medical Units and Pulmonary Ward of Liaquat University Teaching Hospital, Jamshoro / Hyderabad from January till June, 2016.
RESULTS: The majority of cases with COPD were male representing 81.6% of the sample population, almost 90% of patients were smokers or ex-smokers, 42.50% of COPD patients were suffering from DM and 76.47% were either non-compliant or had a very poor control over their blood glucose level. Blood glucose levels of most of the patients was from 140 mg/dl to 500 mg/dl and 19.60% of patients reached diabetic ketoacidosis (DKA) once at least.
CONCLUSION: DM increases the risk for occurrence of COPD and cause rapid decline in clinical state of the patient. Unlike cardiovascular complication of diabetes in case of diabetic patients with COPD the lower the BMI the higher the risk of mortality. |
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| id | doaj.art-20c36f4038e3489c969cc7621a19f62f |
| institution | Directory Open Access Journal |
| issn | 1729-0341 2309-8627 |
| language | English |
| last_indexed | 2024-03-13T07:15:44Z |
| publishDate | 2017-03-01 |
| publisher | Liaquat University of Medical and Health Sciences |
| record_format | Article |
| series | JLUMHS |
| spelling | doaj.art-20c36f4038e3489c969cc7621a19f62f2023-06-05T06:45:32ZengLiaquat University of Medical and Health SciencesJLUMHS1729-03412309-86272017-03-01161414810.22442/jlumhs.171610504Pathophysiological Correlation between Diabetes Mellitus Type-II and Chronic Obstructive Pulmonary DiseasesAhmad N. Bitar 0 Muhammad Ali Ghoto1 Abdullah Dayo2Mudassar Iqbal Arain3Rabia Parveen4University of Sindh, Jamshoro, Sindh-PakistanUniversity of Sindh, Jamshoro, Sindh-PakistanUniversity of Sindh, Jamshoro, Sindh-PakistanUniversity of Sindh, Jamshoro, Sindh-PakistanUniversity of Sindh, Jamshoro, Sindh-PakistanINTRODUCTION: Diabetes Mellitus, a chronic disease is usually associated and linked to many other conditions and complications. Chronic Obstructive Pulmonary Disease (COPD); a life threatening progressive inflammatory lung disease associated with chronic bronchitis and emphysema; when associated with Diabetes Mellitus generates a huge burden on patients quality of life as well as on health care systems. OBJECTIVE: Although link between DM and COPD is not scientifically established or confirmed yet, however evidence suggest a pathophysiological correlation between both conditions might be present. This study focuses upon impact of DM on the onset of COPD and to find if there is any evidence of the suggested pathophysiological correlation. METHODOLOGY: We retrospectively analyzed 120 cases of Chronic Obstructive Pulmonary Disease (COPD), data collected from General Medical Units and Pulmonary Ward of Liaquat University Teaching Hospital, Jamshoro / Hyderabad from January till June, 2016. RESULTS: The majority of cases with COPD were male representing 81.6% of the sample population, almost 90% of patients were smokers or ex-smokers, 42.50% of COPD patients were suffering from DM and 76.47% were either non-compliant or had a very poor control over their blood glucose level. Blood glucose levels of most of the patients was from 140 mg/dl to 500 mg/dl and 19.60% of patients reached diabetic ketoacidosis (DKA) once at least. CONCLUSION: DM increases the risk for occurrence of COPD and cause rapid decline in clinical state of the patient. Unlike cardiovascular complication of diabetes in case of diabetic patients with COPD the lower the BMI the higher the risk of mortality.https://www.lumhs.edu.pk/jlumhs/Vol16No01/pdfs/09.pdf: diabetes miletus (dm)chronic obstructive pulmonary diseases (copd)pathophysiological correlation. |
| spellingShingle | Ahmad N. Bitar Muhammad Ali Ghoto Abdullah Dayo Mudassar Iqbal Arain Rabia Parveen Pathophysiological Correlation between Diabetes Mellitus Type-II and Chronic Obstructive Pulmonary Diseases JLUMHS : diabetes miletus (dm) chronic obstructive pulmonary diseases (copd) pathophysiological correlation. |
| title | Pathophysiological Correlation between Diabetes Mellitus Type-II and Chronic Obstructive Pulmonary Diseases |
| title_full | Pathophysiological Correlation between Diabetes Mellitus Type-II and Chronic Obstructive Pulmonary Diseases |
| title_fullStr | Pathophysiological Correlation between Diabetes Mellitus Type-II and Chronic Obstructive Pulmonary Diseases |
| title_full_unstemmed | Pathophysiological Correlation between Diabetes Mellitus Type-II and Chronic Obstructive Pulmonary Diseases |
| title_short | Pathophysiological Correlation between Diabetes Mellitus Type-II and Chronic Obstructive Pulmonary Diseases |
| title_sort | pathophysiological correlation between diabetes mellitus type ii and chronic obstructive pulmonary diseases |
| topic | : diabetes miletus (dm) chronic obstructive pulmonary diseases (copd) pathophysiological correlation. |
| url | https://www.lumhs.edu.pk/jlumhs/Vol16No01/pdfs/09.pdf |
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