The Role of Lifestyle Interventions in the Prevention and Treatment of Gestational Diabetes Mellitus

Gestational diabetes mellitus (GDM) is one of the most common pregnancy-related endocrinopathies, affecting up to 25% of pregnancies globally. GDM increases the risk of perinatal and delivery complications, and the chance of developing type 2 diabetes mellitus and its complications, including cardio...

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Main Authors: Hala Zakaria, Salah Abusanana, Bashair M. Mussa, Ayesha S. Al Dhaheri, Lily Stojanovska, Maysm N. Mohamad, Sheima T. Saleh, Habiba I. Ali, Leila Cheikh Ismail
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/59/2/287
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author Hala Zakaria
Salah Abusanana
Bashair M. Mussa
Ayesha S. Al Dhaheri
Lily Stojanovska
Maysm N. Mohamad
Sheima T. Saleh
Habiba I. Ali
Leila Cheikh Ismail
author_facet Hala Zakaria
Salah Abusanana
Bashair M. Mussa
Ayesha S. Al Dhaheri
Lily Stojanovska
Maysm N. Mohamad
Sheima T. Saleh
Habiba I. Ali
Leila Cheikh Ismail
author_sort Hala Zakaria
collection DOAJ
description Gestational diabetes mellitus (GDM) is one of the most common pregnancy-related endocrinopathies, affecting up to 25% of pregnancies globally. GDM increases the risk of perinatal and delivery complications, and the chance of developing type 2 diabetes mellitus and its complications, including cardiovascular diseases. This elevated risk is then passed on to the next generation, creating a cycle of metabolic dysfunction across generations. For many years, GDM preventive measures have had inconsistent results, but recent systematic reviews and meta-analyses have identified promising new preventative routes. This review aims to summarize the evidence investigating the efficacy of lifestyle treatments for the prevention of GDM and to summarize the effects of two lifestyle interventions, including physical activity and dietary interventions. Based on the present research, future studies should be conducted to investigate whether initiating lifestyle interventions during the preconception period is more beneficial in preventing GDM. In addition, research targeting pregnancy should be designed with a personalized approach. Therefore, studies should customize intervention approaches depending on the presence of modifiable and non-modifiable risk factors at the individual level.
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spelling doaj.art-20c75c9522be45aaa095c03944ddc8252023-11-16T21:59:42ZengMDPI AGMedicina1010-660X1648-91442023-02-0159228710.3390/medicina59020287The Role of Lifestyle Interventions in the Prevention and Treatment of Gestational Diabetes MellitusHala Zakaria0Salah Abusanana1Bashair M. Mussa2Ayesha S. Al Dhaheri3Lily Stojanovska4Maysm N. Mohamad5Sheima T. Saleh6Habiba I. Ali7Leila Cheikh Ismail8Clinical Science Department, College of Medicine, University of Sharjah, Sharjah 27272, United Arab EmiratesClinical Science Department, College of Medicine, University of Sharjah, Sharjah 27272, United Arab EmiratesClinical Science Department, College of Medicine, University of Sharjah, Sharjah 27272, United Arab EmiratesDepartment of Nutrition and Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab EmiratesDepartment of Nutrition and Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab EmiratesDepartment of Nutrition and Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab EmiratesDepartment of Clinical Nutrition and Dietetics, College of Health Sciences, University of Sharjah, Sharjah 27272, United Arab EmiratesDepartment of Nutrition and Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab EmiratesDepartment of Clinical Nutrition and Dietetics, College of Health Sciences, University of Sharjah, Sharjah 27272, United Arab EmiratesGestational diabetes mellitus (GDM) is one of the most common pregnancy-related endocrinopathies, affecting up to 25% of pregnancies globally. GDM increases the risk of perinatal and delivery complications, and the chance of developing type 2 diabetes mellitus and its complications, including cardiovascular diseases. This elevated risk is then passed on to the next generation, creating a cycle of metabolic dysfunction across generations. For many years, GDM preventive measures have had inconsistent results, but recent systematic reviews and meta-analyses have identified promising new preventative routes. This review aims to summarize the evidence investigating the efficacy of lifestyle treatments for the prevention of GDM and to summarize the effects of two lifestyle interventions, including physical activity and dietary interventions. Based on the present research, future studies should be conducted to investigate whether initiating lifestyle interventions during the preconception period is more beneficial in preventing GDM. In addition, research targeting pregnancy should be designed with a personalized approach. Therefore, studies should customize intervention approaches depending on the presence of modifiable and non-modifiable risk factors at the individual level.https://www.mdpi.com/1648-9144/59/2/287gestational diabetes mellitusGDMlifestyle interventionspreventiondietphysical activity
spellingShingle Hala Zakaria
Salah Abusanana
Bashair M. Mussa
Ayesha S. Al Dhaheri
Lily Stojanovska
Maysm N. Mohamad
Sheima T. Saleh
Habiba I. Ali
Leila Cheikh Ismail
The Role of Lifestyle Interventions in the Prevention and Treatment of Gestational Diabetes Mellitus
Medicina
gestational diabetes mellitus
GDM
lifestyle interventions
prevention
diet
physical activity
title The Role of Lifestyle Interventions in the Prevention and Treatment of Gestational Diabetes Mellitus
title_full The Role of Lifestyle Interventions in the Prevention and Treatment of Gestational Diabetes Mellitus
title_fullStr The Role of Lifestyle Interventions in the Prevention and Treatment of Gestational Diabetes Mellitus
title_full_unstemmed The Role of Lifestyle Interventions in the Prevention and Treatment of Gestational Diabetes Mellitus
title_short The Role of Lifestyle Interventions in the Prevention and Treatment of Gestational Diabetes Mellitus
title_sort role of lifestyle interventions in the prevention and treatment of gestational diabetes mellitus
topic gestational diabetes mellitus
GDM
lifestyle interventions
prevention
diet
physical activity
url https://www.mdpi.com/1648-9144/59/2/287
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