Essential thrombocythemia: Rare cause of chorea

Essential thrombocythemia (ET) is a clonal myeloproliferative disorder (MPD), characterized predominantly by a markedly elevated platelet count without known cause. It is rare hematological disorder. In ET clinical picture is dominated by a predisposition to vascular occlusive events and hemorrhages...

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Main Authors: Eswaradass Prasanna Venkatesan, Kalidoss Ramadoss, Ramasamy Balakrishnan, B Prakash
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Annals of Indian Academy of Neurology
Subjects:
Online Access:http://www.annalsofian.org/article.asp?issn=0972-2327;year=2014;volume=17;issue=1;spage=106;epage=107;aulast=Venkatesan
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author Eswaradass Prasanna Venkatesan
Kalidoss Ramadoss
Ramasamy Balakrishnan
B Prakash
author_facet Eswaradass Prasanna Venkatesan
Kalidoss Ramadoss
Ramasamy Balakrishnan
B Prakash
author_sort Eswaradass Prasanna Venkatesan
collection DOAJ
description Essential thrombocythemia (ET) is a clonal myeloproliferative disorder (MPD), characterized predominantly by a markedly elevated platelet count without known cause. It is rare hematological disorder. In ET clinical picture is dominated by a predisposition to vascular occlusive events and hemorrhages. Headache, transient ischemic attack, stroke, visual disturbances and light headedness are some of the neurological manifestations of ET. Here, we describe a 55 year-old female who presented to us with generalized chorea. On evaluation, she was found to have thrombocytosis. After ruling out the secondary causes of thrombocytosis and other MPD we confirmed diagnosis of ET in her by bone marrow studies. Polycythemia vera (PV) another MPD closely related to ET may be present with generalized chorea. There are few case reports of PV presenting as chorea in the literature, but none with ET. We report the first case of ET presenting as generalized chorea.
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spelling doaj.art-20c9e5104106449988d1c71a0b6e22c52022-12-22T00:16:16ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492014-01-0117110610710.4103/0972-2327.128569Essential thrombocythemia: Rare cause of choreaEswaradass Prasanna VenkatesanKalidoss RamadossRamasamy BalakrishnanB PrakashEssential thrombocythemia (ET) is a clonal myeloproliferative disorder (MPD), characterized predominantly by a markedly elevated platelet count without known cause. It is rare hematological disorder. In ET clinical picture is dominated by a predisposition to vascular occlusive events and hemorrhages. Headache, transient ischemic attack, stroke, visual disturbances and light headedness are some of the neurological manifestations of ET. Here, we describe a 55 year-old female who presented to us with generalized chorea. On evaluation, she was found to have thrombocytosis. After ruling out the secondary causes of thrombocytosis and other MPD we confirmed diagnosis of ET in her by bone marrow studies. Polycythemia vera (PV) another MPD closely related to ET may be present with generalized chorea. There are few case reports of PV presenting as chorea in the literature, but none with ET. We report the first case of ET presenting as generalized chorea.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2014;volume=17;issue=1;spage=106;epage=107;aulast=VenkatesanChoreaessential thrombocythemiapolycythemia vera
spellingShingle Eswaradass Prasanna Venkatesan
Kalidoss Ramadoss
Ramasamy Balakrishnan
B Prakash
Essential thrombocythemia: Rare cause of chorea
Annals of Indian Academy of Neurology
Chorea
essential thrombocythemia
polycythemia vera
title Essential thrombocythemia: Rare cause of chorea
title_full Essential thrombocythemia: Rare cause of chorea
title_fullStr Essential thrombocythemia: Rare cause of chorea
title_full_unstemmed Essential thrombocythemia: Rare cause of chorea
title_short Essential thrombocythemia: Rare cause of chorea
title_sort essential thrombocythemia rare cause of chorea
topic Chorea
essential thrombocythemia
polycythemia vera
url http://www.annalsofian.org/article.asp?issn=0972-2327;year=2014;volume=17;issue=1;spage=106;epage=107;aulast=Venkatesan
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AT ramasamybalakrishnan essentialthrombocythemiararecauseofchorea
AT bprakash essentialthrombocythemiararecauseofchorea