Essential thrombocythemia: Rare cause of chorea
Essential thrombocythemia (ET) is a clonal myeloproliferative disorder (MPD), characterized predominantly by a markedly elevated platelet count without known cause. It is rare hematological disorder. In ET clinical picture is dominated by a predisposition to vascular occlusive events and hemorrhages...
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Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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Series: | Annals of Indian Academy of Neurology |
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Online Access: | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2014;volume=17;issue=1;spage=106;epage=107;aulast=Venkatesan |
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author | Eswaradass Prasanna Venkatesan Kalidoss Ramadoss Ramasamy Balakrishnan B Prakash |
author_facet | Eswaradass Prasanna Venkatesan Kalidoss Ramadoss Ramasamy Balakrishnan B Prakash |
author_sort | Eswaradass Prasanna Venkatesan |
collection | DOAJ |
description | Essential thrombocythemia (ET) is a clonal myeloproliferative disorder (MPD), characterized predominantly by a markedly elevated platelet count without known cause. It is rare hematological disorder. In ET clinical picture is dominated by a predisposition to vascular occlusive events and hemorrhages. Headache, transient ischemic attack, stroke, visual disturbances and light headedness are some of the neurological manifestations of ET. Here, we describe a 55 year-old female who presented to us with generalized chorea. On evaluation, she was found to have thrombocytosis. After ruling out the secondary causes of thrombocytosis and other MPD we confirmed diagnosis of ET in her by bone marrow studies. Polycythemia vera (PV) another MPD closely related to ET may be present with generalized chorea. There are few case reports of PV presenting as chorea in the literature, but none with ET. We report the first case of ET presenting as generalized chorea. |
first_indexed | 2024-12-12T18:15:37Z |
format | Article |
id | doaj.art-20c9e5104106449988d1c71a0b6e22c5 |
institution | Directory Open Access Journal |
issn | 0972-2327 1998-3549 |
language | English |
last_indexed | 2024-12-12T18:15:37Z |
publishDate | 2014-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Annals of Indian Academy of Neurology |
spelling | doaj.art-20c9e5104106449988d1c71a0b6e22c52022-12-22T00:16:16ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492014-01-0117110610710.4103/0972-2327.128569Essential thrombocythemia: Rare cause of choreaEswaradass Prasanna VenkatesanKalidoss RamadossRamasamy BalakrishnanB PrakashEssential thrombocythemia (ET) is a clonal myeloproliferative disorder (MPD), characterized predominantly by a markedly elevated platelet count without known cause. It is rare hematological disorder. In ET clinical picture is dominated by a predisposition to vascular occlusive events and hemorrhages. Headache, transient ischemic attack, stroke, visual disturbances and light headedness are some of the neurological manifestations of ET. Here, we describe a 55 year-old female who presented to us with generalized chorea. On evaluation, she was found to have thrombocytosis. After ruling out the secondary causes of thrombocytosis and other MPD we confirmed diagnosis of ET in her by bone marrow studies. Polycythemia vera (PV) another MPD closely related to ET may be present with generalized chorea. There are few case reports of PV presenting as chorea in the literature, but none with ET. We report the first case of ET presenting as generalized chorea.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2014;volume=17;issue=1;spage=106;epage=107;aulast=VenkatesanChoreaessential thrombocythemiapolycythemia vera |
spellingShingle | Eswaradass Prasanna Venkatesan Kalidoss Ramadoss Ramasamy Balakrishnan B Prakash Essential thrombocythemia: Rare cause of chorea Annals of Indian Academy of Neurology Chorea essential thrombocythemia polycythemia vera |
title | Essential thrombocythemia: Rare cause of chorea |
title_full | Essential thrombocythemia: Rare cause of chorea |
title_fullStr | Essential thrombocythemia: Rare cause of chorea |
title_full_unstemmed | Essential thrombocythemia: Rare cause of chorea |
title_short | Essential thrombocythemia: Rare cause of chorea |
title_sort | essential thrombocythemia rare cause of chorea |
topic | Chorea essential thrombocythemia polycythemia vera |
url | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2014;volume=17;issue=1;spage=106;epage=107;aulast=Venkatesan |
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