Evaluation of dendritic cell-targeting T7 phages as a vehicle to deliver avian influenza virus H5 DNA vaccine in SPF chickens

Evaluation of dendritic cell-targeting T7 phages as a vehicle to deliver avian influenza virus H5 DNA vaccine in SPF chickens

IntroductionThere is a growing demand for effective technologies for the delivery of antigen to antigen-presenting cells (APCs) and their immune-activation for the success of DNA vaccines. Therefore, dendritic cell (DC)-targeting T7 phages were used as a vehicle to deliver DNA vaccine.MethodsIn this...

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Bibliographic Details
Main Authors: Hai Xu, Ling Li, Ruiting Li, Zijie Guo, Mengzhou Lin, Yu Lu, Jibo Hou, Roshini Govinden, Bihua Deng, Hafizah Y. Chenia
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
avian influenza
DNA vaccine
dendritic cell-targeting
T7 phage
SPF chicken
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1063129/full

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