Obesity and reproductive function of women: epigenetic and somato-psychological features
The review article presents data on the effects of obesity on the female reproductive system and offspring of mothers with overweight or obesity, such as infertility, miscarriages, premature birth, stillbirth, congenital anomalies and prematurity, as well as a high risk of cesarean section. Obesity...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2019-09-01
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| Series: | Ожирение и метаболизм |
| Subjects: | |
| Online Access: | https://www.omet-endojournals.ru/jour/article/view/10113 |
| _version_ | 1797204584755625984 |
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| author | Elena N. Andreeva Yulia S. Absatarova Ekaterina V. Sheremetyeva Valentina A. Fursenko |
| author_facet | Elena N. Andreeva Yulia S. Absatarova Ekaterina V. Sheremetyeva Valentina A. Fursenko |
| author_sort | Elena N. Andreeva |
| collection | DOAJ |
| description | The review article presents data on the effects of obesity on the female reproductive system and offspring of mothers with overweight or obesity, such as infertility, miscarriages, premature birth, stillbirth, congenital anomalies and prematurity, as well as a high risk of cesarean section. Obesity accompanies polycystic ovary syndrome, worsening the metabolic profile and increasing the risk of developing depression and eating disorders. Maternal obesity and hyperglycemia are able to influence the formation of the fetus by epigenetic mechanisms without affecting the nucleotide sequences. Subsequently, the metabolic and cardiovascular risks increase in the descendants of obese or overweight mothers and gestational diabetes. Patients with obesity are characterized by a folic acid deficiency and a deficiency of the luteal phase. Exogenous administration of these substances improves pregnancy outcomes and prevents congenital malformations. |
| first_indexed | 2024-03-08T09:12:56Z |
| format | Article |
| id | doaj.art-20cdef6426c1416d84fd11997e6f0e93 |
| institution | Directory Open Access Journal |
| issn | 2071-8713 2306-5524 |
| language | English |
| last_indexed | 2024-04-24T08:37:33Z |
| publishDate | 2019-09-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Ожирение и метаболизм |
| spelling | doaj.art-20cdef6426c1416d84fd11997e6f0e932024-04-16T16:16:12ZengEndocrinology Research CentreОжирение и метаболизм2071-87132306-55242019-09-0116291510.14341/omet101138668Obesity and reproductive function of women: epigenetic and somato-psychological featuresElena N. Andreeva0Yulia S. Absatarova1Ekaterina V. Sheremetyeva2Valentina A. Fursenko3<p>Endocrinology Research Centre; A.I. Yevdokimov Moscow State University of Medicine and Dentistry</p> <p> </p><p>Endocrinology Research Centre</p><p>Endocrinology Research Centre</p><p>Endocrinology Research Centre</p>The review article presents data on the effects of obesity on the female reproductive system and offspring of mothers with overweight or obesity, such as infertility, miscarriages, premature birth, stillbirth, congenital anomalies and prematurity, as well as a high risk of cesarean section. Obesity accompanies polycystic ovary syndrome, worsening the metabolic profile and increasing the risk of developing depression and eating disorders. Maternal obesity and hyperglycemia are able to influence the formation of the fetus by epigenetic mechanisms without affecting the nucleotide sequences. Subsequently, the metabolic and cardiovascular risks increase in the descendants of obese or overweight mothers and gestational diabetes. Patients with obesity are characterized by a folic acid deficiency and a deficiency of the luteal phase. Exogenous administration of these substances improves pregnancy outcomes and prevents congenital malformations.https://www.omet-endojournals.ru/jour/article/view/10113obesityoverweightpolycystic ovary syndromegestational diabetesepigeneticsintrauterine programmingovarian dysfunction |
| spellingShingle | Elena N. Andreeva Yulia S. Absatarova Ekaterina V. Sheremetyeva Valentina A. Fursenko Obesity and reproductive function of women: epigenetic and somato-psychological features Ожирение и метаболизм obesity overweight polycystic ovary syndrome gestational diabetes epigenetics intrauterine programming ovarian dysfunction |
| title | Obesity and reproductive function of women: epigenetic and somato-psychological features |
| title_full | Obesity and reproductive function of women: epigenetic and somato-psychological features |
| title_fullStr | Obesity and reproductive function of women: epigenetic and somato-psychological features |
| title_full_unstemmed | Obesity and reproductive function of women: epigenetic and somato-psychological features |
| title_short | Obesity and reproductive function of women: epigenetic and somato-psychological features |
| title_sort | obesity and reproductive function of women epigenetic and somato psychological features |
| topic | obesity overweight polycystic ovary syndrome gestational diabetes epigenetics intrauterine programming ovarian dysfunction |
| url | https://www.omet-endojournals.ru/jour/article/view/10113 |
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