PES1 promotes BET inhibitors resistance and cells proliferation through increasing c-Myc expression in pancreatic cancer

PES1 promotes BET inhibitors resistance and cells proliferation through increasing c-Myc expression in pancreatic cancer

Abstracts Background Overexpressed PES1 promotes carcinogenesis in various types of malignant tumors. However, the biological role and clinical significance of PES1 in pancreatic cancer are still unexplored. Methods The expression level of PES1 in pancreatic cancer cell lines and pancreatic cancer p...

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Bibliographic Details
Main Authors: Xin Jin, Rui Fang, Ping Fan, Lipeng Zeng, Bin Zhang, Xiaoming Lu, Tao Liu
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
PES1
BRD4
C-Myc
CDK5
Pancreatic cancer
Online Access:http://link.springer.com/article/10.1186/s13046-019-1466-7

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