On the Physical Stability of Leucine-Containing Spray-Dried Powders for Respiratory Drug Delivery

On the Physical Stability of Leucine-Containing Spray-Dried Powders for Respiratory Drug Delivery

Carrier-free spray-dried dispersions for pulmonary delivery, for which the demand is growing, frequently require the incorporation of dispersibility-enhancing excipients into the formulations to improve the efficacy of the dosage form. One of the most promising of such excipients, L-leucine, is expe...

Full description

Bibliographic Details
Main Authors: Mani Ordoubadi, Kimberly B. Shepard, Hui Wang, Zheng Wang, Amanda M. Pluntze, Joseph P. Churchman, Reinhard Vehring
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
spray drying
L-leucine
dry powder inhalers
fibers
powder stability
Online Access:https://www.mdpi.com/1999-4923/15/2/435

Similar Items

Similar Items