Coordinated single-cell tumor microenvironment dynamics reinforce pancreatic cancer subtype

Coordinated single-cell tumor microenvironment dynamics reinforce pancreatic cancer subtype

Abstract Bulk analyses of pancreatic ductal adenocarcinoma (PDAC) samples are complicated by the tumor microenvironment (TME), i.e. signals from fibroblasts, endocrine, exocrine, and immune cells. Despite this, we and others have established tumor and stroma subtypes with prognostic significance. Ho...

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Bibliographic Details
Main Authors:	Ki Oh, Yun Jae Yoo, Luke A. Torre-Healy, Manisha Rao, Danielle Fassler, Pei Wang, Michael Caponegro, Mei Gao, Joseph Kim, Aaron Sasson, Georgios Georgakis, Scott Powers, Richard A. Moffitt
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-08-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-023-40895-6

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