Evaluating active versus passive sources of human brucellosis in Jining City, China
Human brucellosis (HB) remains a serious public health concern owing to its resurgence across the globe and specifically in China. The timely detection of this disease is the key to its prevention and control. We sought to describe the differences in the demographics of high-risk populations with de...
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PeerJ Inc.
2021-06-01
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| author | Xihong Sun Wenguo Jiang Yan Li Xiuchun Li Qingyi Zeng Juan Du Aitian Yin Qing-Bin Lu |
| author_facet | Xihong Sun Wenguo Jiang Yan Li Xiuchun Li Qingyi Zeng Juan Du Aitian Yin Qing-Bin Lu |
| author_sort | Xihong Sun |
| collection | DOAJ |
| description | Human brucellosis (HB) remains a serious public health concern owing to its resurgence across the globe and specifically in China. The timely detection of this disease is the key to its prevention and control. We sought to describe the differences in the demographics of high-risk populations with detected cases of HB contracted from active versus passive sources. We collected data from a large sample population from January to December 2018, in Jining City, China. We recruited patients that were at high-risk for brucellosis from three hospitals and Centers of Disease Control and Prevention (CDCs). These patients were classified into two groups: the active detection group was composed of individuals receiving brucellosis counseling at the CDCs; the passive detection group came from hospitals and high-risk HB groups. We tested a total of 2,247 subjects and 13.3% (299) presented as positive for HB. The positive rates for active and passive detection groups were 20.5% (256/1,249) and 4.3% (43/998), respectively (p < 0.001). The detection rate of confirmed HB cases varied among all groups but was higher in the active detection group than in the passive detection group when controlled for age, sex, ethnicity, education, career, and contact history with sheep or cattle (p < 0.05). Males, farmers, those with four types of contact history with sheep or cattle, and those presenting fever, hyperhidrosis and muscle pain were independent factors associated with confirmed HB cases in multivariate analysis of the active detection group. Active detection is the most common method used to detect brucellosis cases and should be applied to detect HB cases early and avoid misdiagnosis. We need to improve our understanding of brucellosis for high-risk populations. Passive HB detection can be supplemented with active detection when the cognitive changes resulting from brucellosis are low. It is important that healthcare providers understand and emphasis the timely diagnosis of HB. |
| first_indexed | 2024-03-09T07:53:18Z |
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| language | English |
| last_indexed | 2024-03-09T07:53:18Z |
| publishDate | 2021-06-01 |
| publisher | PeerJ Inc. |
| record_format | Article |
| series | PeerJ |
| spelling | doaj.art-20d70b7434c7406ea756a76cd223b9f72023-12-03T01:21:55ZengPeerJ Inc.PeerJ2167-83592021-06-019e1163710.7717/peerj.11637Evaluating active versus passive sources of human brucellosis in Jining City, ChinaXihong Sun0Wenguo Jiang1Yan Li2Xiuchun Li3Qingyi Zeng4Juan Du5Aitian Yin6Qing-Bin Lu7Centre for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong University, NHC Key Laboratory of Health Economics and Policy Research (Shandong University), Jinan, Shandong, ChinaJining Center for Disease Control and Prevention, Jining, Shandong, ChinaJining Center for Disease Control and Prevention, Jining, Shandong, ChinaLiangshan Center for Disease Control and Prevention, Jining, Shandong, ChinaYutai Center for Disease Control and Prevention, Jining, Shandong, ChinaLaboratorial Science and Technology, School of Public Health, Peking University, Beijing, ChinaCentre for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong University, NHC Key Laboratory of Health Economics and Policy Research (Shandong University), Jinan, Shandong, ChinaLaboratorial Science and Technology, School of Public Health, Peking University, Beijing, ChinaHuman brucellosis (HB) remains a serious public health concern owing to its resurgence across the globe and specifically in China. The timely detection of this disease is the key to its prevention and control. We sought to describe the differences in the demographics of high-risk populations with detected cases of HB contracted from active versus passive sources. We collected data from a large sample population from January to December 2018, in Jining City, China. We recruited patients that were at high-risk for brucellosis from three hospitals and Centers of Disease Control and Prevention (CDCs). These patients were classified into two groups: the active detection group was composed of individuals receiving brucellosis counseling at the CDCs; the passive detection group came from hospitals and high-risk HB groups. We tested a total of 2,247 subjects and 13.3% (299) presented as positive for HB. The positive rates for active and passive detection groups were 20.5% (256/1,249) and 4.3% (43/998), respectively (p < 0.001). The detection rate of confirmed HB cases varied among all groups but was higher in the active detection group than in the passive detection group when controlled for age, sex, ethnicity, education, career, and contact history with sheep or cattle (p < 0.05). Males, farmers, those with four types of contact history with sheep or cattle, and those presenting fever, hyperhidrosis and muscle pain were independent factors associated with confirmed HB cases in multivariate analysis of the active detection group. Active detection is the most common method used to detect brucellosis cases and should be applied to detect HB cases early and avoid misdiagnosis. We need to improve our understanding of brucellosis for high-risk populations. Passive HB detection can be supplemented with active detection when the cognitive changes resulting from brucellosis are low. It is important that healthcare providers understand and emphasis the timely diagnosis of HB.https://peerj.com/articles/11637.pdfHuman brucellosisActive and passive sourcesContact historyChina |
| spellingShingle | Xihong Sun Wenguo Jiang Yan Li Xiuchun Li Qingyi Zeng Juan Du Aitian Yin Qing-Bin Lu Evaluating active versus passive sources of human brucellosis in Jining City, China PeerJ Human brucellosis Active and passive sources Contact history China |
| title | Evaluating active versus passive sources of human brucellosis in Jining City, China |
| title_full | Evaluating active versus passive sources of human brucellosis in Jining City, China |
| title_fullStr | Evaluating active versus passive sources of human brucellosis in Jining City, China |
| title_full_unstemmed | Evaluating active versus passive sources of human brucellosis in Jining City, China |
| title_short | Evaluating active versus passive sources of human brucellosis in Jining City, China |
| title_sort | evaluating active versus passive sources of human brucellosis in jining city china |
| topic | Human brucellosis Active and passive sources Contact history China |
| url | https://peerj.com/articles/11637.pdf |
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