Pulsed Hyperoxia Acts on Plasmatic Advanced Glycation End Products and Advanced Oxidation Protein Products and Modulates Mitochondrial Biogenesis in Human Peripheral Blood Mononuclear Cells: A Pilot Study on the “Normobaric Oxygen Paradox”

Pulsed Hyperoxia Acts on Plasmatic Advanced Glycation End Products and Advanced Oxidation Protein Products and Modulates Mitochondrial Biogenesis in Human Peripheral Blood Mononuclear Cells: A Pilot Study on the “Normobaric Oxygen Paradox”

The “normobaric oxygen paradox” (NOP) describes the response to the return to normoxia after a hyperoxic event, sensed by tissues as an oxygen shortage, up-regulating redox-sensitive transcription factors. We have previously characterized the time trend of oxygen-sensitive transcription factors in h...

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Bibliographic Details
Main Authors: Costantino Balestra, Sara Baldelli, Fabio Virgili, Michele Salvagno, Simona Mrakic-Sposta, Deborah Fratantonio
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
human
peripheral blood mononuclear cells (PBMCs)
reactive oxygen species (ROS)
oxidative stress
Nrf2
PGC-1α
Online Access:https://www.mdpi.com/1422-0067/25/4/2394

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