Identification of the Kinase-Substrate Recognition Interface between MYPT1 and Rho-Kinase

Identification of the Kinase-Substrate Recognition Interface between MYPT1 and Rho-Kinase

Protein kinases exert physiological functions through phosphorylating their specific substrates; however, the mode of kinase–substrate recognition is not fully understood. Rho-kinase is a Ser/Thr protein kinase that regulates cytoskeletal reorganization through phosphorylating myosin light chain (ML...

Full description

Bibliographic Details
Main Authors: Mutsuki Amano, Yoko Kanazawa, Kei Kozawa, Kozo Kaibuchi
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomolecules
Subjects:
Rho-kinase
MYPT1
phosphorylation
substrate recognition
interface
docking motif
Online Access:https://www.mdpi.com/2218-273X/12/2/159

Similar Items

Similar Items