Exploring the Impact of Model-Informed Precision Dosing on Procalcitonin Concentrations in Critically Ill Patients: A Secondary Analysis of the DOLPHIN Trial

Exploring the Impact of Model-Informed Precision Dosing on Procalcitonin Concentrations in Critically Ill Patients: A Secondary Analysis of the DOLPHIN Trial

Model-informed precision dosing (MIPD) might be used to optimize antibiotic treatment. Procalcitonin (PCT) is a biomarker for severity of infection and response to antibiotic treatment. The aim of this study was to assess the impact of MIPD on the course of PCT and to investigate the association of...

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Hlavní autoři: Sarah Dräger, Tim M. J. Ewoldt, Alan Abdulla, Wim J. R. Rietdijk, Nelianne Verkaik, Christian Ramakers, Evelien de Jong, Michael Osthoff, Birgit C. P. Koch, Henrik Endeman
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2024-02-01
Edice:Pharmaceutics
Témata:
model-informed precision dosing
procalcitonin
inflammation
biomarker
antibiotics
critically ill
On-line přístup:https://www.mdpi.com/1999-4923/16/2/270

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https://www.mdpi.com/1999-4923/16/2/270

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