Detailed characterisation of invasive aspergillosis in a murine model of X-linked chronic granulomatous disease shows new insights in infections caused by Aspergillus fumigatus versus Aspergillus nidulans

Detailed characterisation of invasive aspergillosis in a murine model of X-linked chronic granulomatous disease shows new insights in infections caused by Aspergillus fumigatus versus Aspergillus nidulans

IntroductionInvasive aspergillosis (IA) is the most prevalent infectious complication in patients with chronic granulomatous disease (CGD). Yet, understanding of fungal pathogenesis in the CGD host remains limited, particularly with regards to A. nidulans infection.MethodsWe have used a murine model...

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Bibliographic Details
Main Authors: Jill King, Ivy M. Dambuza, Delyth M. Reid, Raif Yuecel, Gordon D. Brown, Adilia Warris
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
chronic granulomatous disease
Aspergillus fumigatus
Aspergillus nidulans
murine
infection
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1241770/full

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