Alteration of <i>Salmonella enterica</i> Virulence and Host Pathogenesis through Targeting <i>sdiA</i> by Using the CRISPR-Cas9 System

Alteration of <i>Salmonella enterica</i> Virulence and Host Pathogenesis through Targeting <i>sdiA</i> by Using the CRISPR-Cas9 System

<i>Salmonella enterica</i> is a common cause of many enteric infections worldwide and is successfully engineered to deliver heterologous antigens to be used as vaccines. Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) RNA-guided Cas9 endonuclease is a promising genome...

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Bibliographic Details
Main Authors: Momen Askoura, Ahmad J. Almalki, Amr S. Abu Lila, Khaled Almansour, Farhan Alshammari, El-Sayed Khafagy, Tarek S. Ibrahim, Wael A. H. Hegazy
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Microorganisms
Subjects:
<i>Salmonella enterica</i>
CRISPR-Cas9
<i>sdiA</i>
<i>ssaV</i>
virulence
pathogenesis
Online Access:https://www.mdpi.com/2076-2607/9/12/2564

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