Anti-diabetic Activity of Tabat Barito Leafs (Ficus deltoidea, Jack) Extract in Rats

Tabat barito (<em>Ficus deltoidea</em>, Jack) leaf is believed could be used to treat diabetes. But more scientific data are needed. The aim of this study is to investigate  antidiabetic activity of  Tabat Barito extract by glucose tolerance method. The treatment was given in three doses...

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Main Authors: Heru Agus Cahyanto, Nana Supriyatna
Format: Article
Language:Indonesian
Published: Balai Riset dan Standardisasi Industri Pontianak 2013-06-01
Series:Biopropal Industri
Subjects:
Online Access:http://ejournal.kemenperin.go.id/biopropal/article/view/805
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author Heru Agus Cahyanto
Nana Supriyatna
author_facet Heru Agus Cahyanto
Nana Supriyatna
author_sort Heru Agus Cahyanto
collection DOAJ
description Tabat barito (<em>Ficus deltoidea</em>, Jack) leaf is believed could be used to treat diabetes. But more scientific data are needed. The aim of this study is to investigate  antidiabetic activity of  Tabat Barito extract by glucose tolerance method. The treatment was given in three doses (50, 100, and 200 mg/kg BW) and two controls using aquoeus and glibenklamid.  Tabat barito extract was obtained by maceration and made into dry extract with addition of starch. The result showed that chemical compound of the ethanol extract were fenolic and saponin. The extract showed effects in lowering blood sugar levels with glucose tolerance methods at 30 to 60 minutes. Blood glucose levels of mice treated with the extract extract ranged between 132.60 to 258.00 mg/dL , glibenklamide ranged from 130.20 to 144.60 mg/dL, and aqua ranged between 227.60 to 260.20 mg/dL. The percentage decrease in blood sugar levels compared to controls is 32.54%.
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spelling doaj.art-20e5865513044732ab5151fa689b3a072022-12-22T03:04:43ZindBalai Riset dan Standardisasi Industri PontianakBiopropal Industri2089-08772502-29622013-06-0141726Anti-diabetic Activity of Tabat Barito Leafs (Ficus deltoidea, Jack) Extract in RatsHeru Agus Cahyanto0Nana Supriyatna1Baristand Industri Pontianak, Jl. Budi Utomo No.41 PontianakBaristand Industri Pontianak, Jl. Budi Utomo No.41 PontianakTabat barito (<em>Ficus deltoidea</em>, Jack) leaf is believed could be used to treat diabetes. But more scientific data are needed. The aim of this study is to investigate  antidiabetic activity of  Tabat Barito extract by glucose tolerance method. The treatment was given in three doses (50, 100, and 200 mg/kg BW) and two controls using aquoeus and glibenklamid.  Tabat barito extract was obtained by maceration and made into dry extract with addition of starch. The result showed that chemical compound of the ethanol extract were fenolic and saponin. The extract showed effects in lowering blood sugar levels with glucose tolerance methods at 30 to 60 minutes. Blood glucose levels of mice treated with the extract extract ranged between 132.60 to 258.00 mg/dL , glibenklamide ranged from 130.20 to 144.60 mg/dL, and aqua ranged between 227.60 to 260.20 mg/dL. The percentage decrease in blood sugar levels compared to controls is 32.54%.http://ejournal.kemenperin.go.id/biopropal/article/view/805diabeticoral glucose tolerancetabat barito
spellingShingle Heru Agus Cahyanto
Nana Supriyatna
Anti-diabetic Activity of Tabat Barito Leafs (Ficus deltoidea, Jack) Extract in Rats
Biopropal Industri
diabetic
oral glucose tolerance
tabat barito
title Anti-diabetic Activity of Tabat Barito Leafs (Ficus deltoidea, Jack) Extract in Rats
title_full Anti-diabetic Activity of Tabat Barito Leafs (Ficus deltoidea, Jack) Extract in Rats
title_fullStr Anti-diabetic Activity of Tabat Barito Leafs (Ficus deltoidea, Jack) Extract in Rats
title_full_unstemmed Anti-diabetic Activity of Tabat Barito Leafs (Ficus deltoidea, Jack) Extract in Rats
title_short Anti-diabetic Activity of Tabat Barito Leafs (Ficus deltoidea, Jack) Extract in Rats
title_sort anti diabetic activity of tabat barito leafs ficus deltoidea jack extract in rats
topic diabetic
oral glucose tolerance
tabat barito
url http://ejournal.kemenperin.go.id/biopropal/article/view/805
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AT nanasupriyatna antidiabeticactivityoftabatbaritoleafsficusdeltoideajackextractinrats