Gypenosides ameliorate morphine-induced immunosuppression with an increased proportion of thymic T lymphocyte subsets and are involved in the regulation of the cAMP-CREM/CREB-IL-2 pathway
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2024-05-01
|
Series: | Genes and Diseases |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352304223003306 |
_version_ | 1797295192671256576 |
---|---|
author | Hui Wang Zhonghao Li Qisheng Wang Weixin Lin Ziting Zhou Xinru Mu Yongwei Jiang Shengfeng Lu Shaodong Chen Zhigang Lu |
author_facet | Hui Wang Zhonghao Li Qisheng Wang Weixin Lin Ziting Zhou Xinru Mu Yongwei Jiang Shengfeng Lu Shaodong Chen Zhigang Lu |
author_sort | Hui Wang |
collection | DOAJ |
first_indexed | 2024-03-07T21:43:13Z |
format | Article |
id | doaj.art-20e96e5aa6c84f52952e2dfe74e5cbce |
institution | Directory Open Access Journal |
issn | 2352-3042 |
language | English |
last_indexed | 2024-03-07T21:43:13Z |
publishDate | 2024-05-01 |
publisher | KeAi Communications Co., Ltd. |
record_format | Article |
series | Genes and Diseases |
spelling | doaj.art-20e96e5aa6c84f52952e2dfe74e5cbce2024-02-26T04:15:53ZengKeAi Communications Co., Ltd.Genes and Diseases2352-30422024-05-01113101049Gypenosides ameliorate morphine-induced immunosuppression with an increased proportion of thymic T lymphocyte subsets and are involved in the regulation of the cAMP-CREM/CREB-IL-2 pathwayHui Wang0Zhonghao Li1Qisheng Wang2Weixin Lin3Ziting Zhou4Xinru Mu5Yongwei Jiang6Shengfeng Lu7Shaodong Chen8Zhigang Lu9Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine in Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, ChinaJiangsu Collaborative Innovation Center of Traditional Chinese Medicine in Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, ChinaJiangsu Collaborative Innovation Center of Traditional Chinese Medicine in Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, ChinaJiangsu Collaborative Innovation Center of Traditional Chinese Medicine in Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, ChinaJiangsu Collaborative Innovation Center of Traditional Chinese Medicine in Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, ChinaJiangsu Collaborative Innovation Center of Traditional Chinese Medicine in Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, ChinaKey Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, ChinaKey Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, ChinaSchool of Medicine, Xiamen University, Xiamen, Fujian 361102, China; Corresponding author.Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine in Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China; Corresponding author. Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine in Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China.http://www.sciencedirect.com/science/article/pii/S2352304223003306 |
spellingShingle | Hui Wang Zhonghao Li Qisheng Wang Weixin Lin Ziting Zhou Xinru Mu Yongwei Jiang Shengfeng Lu Shaodong Chen Zhigang Lu Gypenosides ameliorate morphine-induced immunosuppression with an increased proportion of thymic T lymphocyte subsets and are involved in the regulation of the cAMP-CREM/CREB-IL-2 pathway Genes and Diseases |
title | Gypenosides ameliorate morphine-induced immunosuppression with an increased proportion of thymic T lymphocyte subsets and are involved in the regulation of the cAMP-CREM/CREB-IL-2 pathway |
title_full | Gypenosides ameliorate morphine-induced immunosuppression with an increased proportion of thymic T lymphocyte subsets and are involved in the regulation of the cAMP-CREM/CREB-IL-2 pathway |
title_fullStr | Gypenosides ameliorate morphine-induced immunosuppression with an increased proportion of thymic T lymphocyte subsets and are involved in the regulation of the cAMP-CREM/CREB-IL-2 pathway |
title_full_unstemmed | Gypenosides ameliorate morphine-induced immunosuppression with an increased proportion of thymic T lymphocyte subsets and are involved in the regulation of the cAMP-CREM/CREB-IL-2 pathway |
title_short | Gypenosides ameliorate morphine-induced immunosuppression with an increased proportion of thymic T lymphocyte subsets and are involved in the regulation of the cAMP-CREM/CREB-IL-2 pathway |
title_sort | gypenosides ameliorate morphine induced immunosuppression with an increased proportion of thymic t lymphocyte subsets and are involved in the regulation of the camp crem creb il 2 pathway |
url | http://www.sciencedirect.com/science/article/pii/S2352304223003306 |
work_keys_str_mv | AT huiwang gypenosidesamelioratemorphineinducedimmunosuppressionwithanincreasedproportionofthymictlymphocytesubsetsandareinvolvedintheregulationofthecampcremcrebil2pathway AT zhonghaoli gypenosidesamelioratemorphineinducedimmunosuppressionwithanincreasedproportionofthymictlymphocytesubsetsandareinvolvedintheregulationofthecampcremcrebil2pathway AT qishengwang gypenosidesamelioratemorphineinducedimmunosuppressionwithanincreasedproportionofthymictlymphocytesubsetsandareinvolvedintheregulationofthecampcremcrebil2pathway AT weixinlin gypenosidesamelioratemorphineinducedimmunosuppressionwithanincreasedproportionofthymictlymphocytesubsetsandareinvolvedintheregulationofthecampcremcrebil2pathway AT zitingzhou gypenosidesamelioratemorphineinducedimmunosuppressionwithanincreasedproportionofthymictlymphocytesubsetsandareinvolvedintheregulationofthecampcremcrebil2pathway AT xinrumu gypenosidesamelioratemorphineinducedimmunosuppressionwithanincreasedproportionofthymictlymphocytesubsetsandareinvolvedintheregulationofthecampcremcrebil2pathway AT yongweijiang gypenosidesamelioratemorphineinducedimmunosuppressionwithanincreasedproportionofthymictlymphocytesubsetsandareinvolvedintheregulationofthecampcremcrebil2pathway AT shengfenglu gypenosidesamelioratemorphineinducedimmunosuppressionwithanincreasedproportionofthymictlymphocytesubsetsandareinvolvedintheregulationofthecampcremcrebil2pathway AT shaodongchen gypenosidesamelioratemorphineinducedimmunosuppressionwithanincreasedproportionofthymictlymphocytesubsetsandareinvolvedintheregulationofthecampcremcrebil2pathway AT zhiganglu gypenosidesamelioratemorphineinducedimmunosuppressionwithanincreasedproportionofthymictlymphocytesubsetsandareinvolvedintheregulationofthecampcremcrebil2pathway |