Drug cocktail optimization in chemotherapy of cancer.
BACKGROUND: In general, drug metabolism has to be considered to avoid adverse effects and ineffective therapy. In particular, chemotherapeutic drug cocktails strain drug metabolizing enzymes especially the cytochrome P450 family (CYP). Furthermore, a number of important chemotherapeutic drugs such a...
Main Authors: | Saskia Preissner, Mathias Dunkel, Michael F Hoffmann, Sarah C Preissner, Nikolai Genov, Wen Wei Rong, Robert Preissner, Karlheinz Seeger |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3517625?pdf=render |
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