Stage 5 retinopathy of prematurity: An update

Retinopathy of prematurity (ROP) is one of the most common causes of preventable blindness in children. In spite of the availability of various treatment options, and favorable results with timely intervention, many infants present to the ophthalmologists in the advanced end stage of the disease due...

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Main Authors: Parveen Sen, Smriti Jain, Pramod Bhende
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Taiwan Journal of Ophthalmology
Subjects:
Online Access:http://www.e-tjo.org/article.asp?issn=2211-5056;year=2018;volume=8;issue=4;spage=205;epage=215;aulast=Sen
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author Parveen Sen
Smriti Jain
Pramod Bhende
author_facet Parveen Sen
Smriti Jain
Pramod Bhende
author_sort Parveen Sen
collection DOAJ
description Retinopathy of prematurity (ROP) is one of the most common causes of preventable blindness in children. In spite of the availability of various treatment options, and favorable results with timely intervention, many infants present to the ophthalmologists in the advanced end stage of the disease due to lack of awareness especially in the developing nations. This blinding or Stage 5 of ROP presents with total retinal detachment and has to be managed surgically. The surgical techniques for Stage 5 ROP are unique and demanding. The successful anatomical results after surgery are only seen in 20%–50% of cases. In spite of a successful anatomical result, the visual outcome may be slow and limited. The use of newer pharmacological adjuncts has shown promising results. Because of heterogeneity of presentation of the disease severity, a genetic predisposition has also been proposed. A concerted effort from the pediatricians, ophthalmologists, and healthcare workers is required to establish effective screening and treatment guidelines to prevent blindness due to ROP. Till then surgical management has to be done. Parents must be educated regarding the limited visual benefits of surgery and the need for prolonged follow-up. This review gives a comprehensive overview of the pathogenesis, clinical aspects, surgical interventions, and their outcomes and future prospects of Stage 5 ROP.
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spelling doaj.art-20eb3f9c6cbe4d18a70c34dec7a41f1d2022-12-21T17:51:14ZengWolters Kluwer Medknow PublicationsTaiwan Journal of Ophthalmology2211-50562211-50722018-01-018420521510.4103/tjo.tjo_61_18Stage 5 retinopathy of prematurity: An updateParveen SenSmriti JainPramod BhendeRetinopathy of prematurity (ROP) is one of the most common causes of preventable blindness in children. In spite of the availability of various treatment options, and favorable results with timely intervention, many infants present to the ophthalmologists in the advanced end stage of the disease due to lack of awareness especially in the developing nations. This blinding or Stage 5 of ROP presents with total retinal detachment and has to be managed surgically. The surgical techniques for Stage 5 ROP are unique and demanding. The successful anatomical results after surgery are only seen in 20%–50% of cases. In spite of a successful anatomical result, the visual outcome may be slow and limited. The use of newer pharmacological adjuncts has shown promising results. Because of heterogeneity of presentation of the disease severity, a genetic predisposition has also been proposed. A concerted effort from the pediatricians, ophthalmologists, and healthcare workers is required to establish effective screening and treatment guidelines to prevent blindness due to ROP. Till then surgical management has to be done. Parents must be educated regarding the limited visual benefits of surgery and the need for prolonged follow-up. This review gives a comprehensive overview of the pathogenesis, clinical aspects, surgical interventions, and their outcomes and future prospects of Stage 5 ROP.http://www.e-tjo.org/article.asp?issn=2211-5056;year=2018;volume=8;issue=4;spage=205;epage=215;aulast=SenAnatomical successcomplicationsfunctional successretrolental fibroplasiasurgical management
spellingShingle Parveen Sen
Smriti Jain
Pramod Bhende
Stage 5 retinopathy of prematurity: An update
Taiwan Journal of Ophthalmology
Anatomical success
complications
functional success
retrolental fibroplasia
surgical management
title Stage 5 retinopathy of prematurity: An update
title_full Stage 5 retinopathy of prematurity: An update
title_fullStr Stage 5 retinopathy of prematurity: An update
title_full_unstemmed Stage 5 retinopathy of prematurity: An update
title_short Stage 5 retinopathy of prematurity: An update
title_sort stage 5 retinopathy of prematurity an update
topic Anatomical success
complications
functional success
retrolental fibroplasia
surgical management
url http://www.e-tjo.org/article.asp?issn=2211-5056;year=2018;volume=8;issue=4;spage=205;epage=215;aulast=Sen
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AT smritijain stage5retinopathyofprematurityanupdate
AT pramodbhende stage5retinopathyofprematurityanupdate