Hypopituitarism as unusual sequelae to central nervous system tuberculosis
Neurological tuberculosis can very rarely involve the hypophysis cerebri. We report a case of an eighteen year old female who presented with five months duration of generalised apathy, secondary amenorrhea and weight gain. She was on irregular treatment for tuberculosis of the central nervous system...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2011-01-01
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| Series: | Indian Journal of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2011;volume=15;issue=7;spage=259;epage=262;aulast=Mageshkumar |
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| author | S Mageshkumar Devendra V Patil J A Philo Aarthy K Madhavan |
| author_facet | S Mageshkumar Devendra V Patil J A Philo Aarthy K Madhavan |
| author_sort | S Mageshkumar |
| collection | DOAJ |
| description | Neurological tuberculosis can very rarely involve the hypophysis cerebri. We report a case of an eighteen year old female who presented with five months duration of generalised apathy, secondary amenorrhea and weight gain. She was on irregular treatment for tuberculosis of the central nervous system for the last five months. Neuroimaging revealed sellar and suprasellar tuberculomas and communicating hydrocephalus requiring emergency decompression. Endocrinological investigation showed hypopituitarism manifesting as pituitary hypothyroidism, hypocortisolism, hypogonadotropic hypogonadism, and hyperprolactinemia. Restarting anti-tuberculosis treatment, hormone replacement therapy, and a ventriculo-peritoneal shunt surgery led to remarkable improvement in the general condition of the patient. |
| first_indexed | 2024-12-11T22:11:43Z |
| format | Article |
| id | doaj.art-20ed3483859342f9aaa2a22de3d28485 |
| institution | Directory Open Access Journal |
| issn | 2230-8210 2230-9500 |
| language | English |
| last_indexed | 2024-12-11T22:11:43Z |
| publishDate | 2011-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-20ed3483859342f9aaa2a22de3d284852022-12-22T00:48:45ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102230-95002011-01-0115725926210.4103/2230-8210.84881Hypopituitarism as unusual sequelae to central nervous system tuberculosisS MageshkumarDevendra V PatilJ A Philo AarthyK MadhavanNeurological tuberculosis can very rarely involve the hypophysis cerebri. We report a case of an eighteen year old female who presented with five months duration of generalised apathy, secondary amenorrhea and weight gain. She was on irregular treatment for tuberculosis of the central nervous system for the last five months. Neuroimaging revealed sellar and suprasellar tuberculomas and communicating hydrocephalus requiring emergency decompression. Endocrinological investigation showed hypopituitarism manifesting as pituitary hypothyroidism, hypocortisolism, hypogonadotropic hypogonadism, and hyperprolactinemia. Restarting anti-tuberculosis treatment, hormone replacement therapy, and a ventriculo-peritoneal shunt surgery led to remarkable improvement in the general condition of the patient.http://www.ijem.in/article.asp?issn=2230-8210;year=2011;volume=15;issue=7;spage=259;epage=262;aulast=MageshkumarHyperprolactinemiahypogonadotropismhypopituitarismtuberculomas |
| spellingShingle | S Mageshkumar Devendra V Patil J A Philo Aarthy K Madhavan Hypopituitarism as unusual sequelae to central nervous system tuberculosis Indian Journal of Endocrinology and Metabolism Hyperprolactinemia hypogonadotropism hypopituitarism tuberculomas |
| title | Hypopituitarism as unusual sequelae to central nervous system tuberculosis |
| title_full | Hypopituitarism as unusual sequelae to central nervous system tuberculosis |
| title_fullStr | Hypopituitarism as unusual sequelae to central nervous system tuberculosis |
| title_full_unstemmed | Hypopituitarism as unusual sequelae to central nervous system tuberculosis |
| title_short | Hypopituitarism as unusual sequelae to central nervous system tuberculosis |
| title_sort | hypopituitarism as unusual sequelae to central nervous system tuberculosis |
| topic | Hyperprolactinemia hypogonadotropism hypopituitarism tuberculomas |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2011;volume=15;issue=7;spage=259;epage=262;aulast=Mageshkumar |
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