Acute respiratory distress syndrome among patients with severe COVID-19 admitted to treatment center of Wollega University Referral Hospital, Western Ethiopia.
<h4>Background</h4>Acute respiratory distress syndrome is a life-threatening condition that has a significant effect on the occurrence of morbidity and mortality among patients with severe Coronavirus disease 2019 (COVID-19). To the best of researchers' knowledge, there is no Study...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0267835 |
| _version_ | 1811217403991818240 |
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| author | Tadesse Tolossa Emiru Merdassa Atomssa Getahun Fetensa Lami Bayisa Diriba Ayala Ebisa Turi Bizuneh Wakuma Diriba Mulisa Dejene Seyoum Ayantu Getahun Tesfaye Shibiru Ginenus Fekadu Markos Desalegn Haile Bikila |
| author_facet | Tadesse Tolossa Emiru Merdassa Atomssa Getahun Fetensa Lami Bayisa Diriba Ayala Ebisa Turi Bizuneh Wakuma Diriba Mulisa Dejene Seyoum Ayantu Getahun Tesfaye Shibiru Ginenus Fekadu Markos Desalegn Haile Bikila |
| author_sort | Tadesse Tolossa |
| collection | DOAJ |
| description | <h4>Background</h4>Acute respiratory distress syndrome is a life-threatening condition that has a significant effect on the occurrence of morbidity and mortality among patients with severe Coronavirus disease 2019 (COVID-19). To the best of researchers' knowledge, there is no Study on ARDS of COVID-19 in Ethiopia. Therefore, this study aimed to identify the prevalence of ARDS and associated factors among severe COVID-19 patients at Wollega University Referral Hospital.<h4>Methods</h4>An institution-based retrospective cross-sectional study was conducted from September 20, 2020, to June 10, 2021. Real-Time Reverse transcription-polymerase Chain Reaction (rRT-PCR) test was used to test Patients for COVID-19. Epi-data version 3.2 was used for data entry, and the final data analysis was through STATA version 14. After checking the assumption P-value<0.25 in the bivariable analysis was used to select a candidate variable for multi-variable analysis, and a p-value of <0.05 was used to declare statistical significance.<h4>Results</h4>In this study, the prevalence of ARDS was 32%. Almost all the patients had the clinical feature of cough (93.7%), followed by shortness of breath (79.9%), fever (77.7%), and headache (67%). Age older than 65 years (AOR = 3.35, 95%CI = 1.31, 8.55), male gender (AOR = 5.63, 95%CI = 2.15, 14.77), and low oxygen saturation level (AOR = 4.60, 95%CI = 1.15, 18.35) were the independent predictors of ARDS among severe COVID-19 patients.<h4>Conclusion</h4>The prevalence of ARDS among patients with severe COVID-19 was high in the study area. Therefore, elders and patients with critical conditions (low oxygen saturation) better to get special attention during COVID-19 case management to enhance good care and monitoring of the patients. |
| first_indexed | 2024-04-12T06:54:33Z |
| format | Article |
| id | doaj.art-20ed8d7df58c4d5ab088a92f348fa7c2 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T06:54:33Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-20ed8d7df58c4d5ab088a92f348fa7c22022-12-22T03:43:12ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01176e026783510.1371/journal.pone.0267835Acute respiratory distress syndrome among patients with severe COVID-19 admitted to treatment center of Wollega University Referral Hospital, Western Ethiopia.Tadesse TolossaEmiru Merdassa AtomssaGetahun FetensaLami BayisaDiriba AyalaEbisa TuriBizuneh WakumaDiriba MulisaDejene SeyoumAyantu GetahunTesfaye ShibiruGinenus FekaduMarkos DesalegnHaile Bikila<h4>Background</h4>Acute respiratory distress syndrome is a life-threatening condition that has a significant effect on the occurrence of morbidity and mortality among patients with severe Coronavirus disease 2019 (COVID-19). To the best of researchers' knowledge, there is no Study on ARDS of COVID-19 in Ethiopia. Therefore, this study aimed to identify the prevalence of ARDS and associated factors among severe COVID-19 patients at Wollega University Referral Hospital.<h4>Methods</h4>An institution-based retrospective cross-sectional study was conducted from September 20, 2020, to June 10, 2021. Real-Time Reverse transcription-polymerase Chain Reaction (rRT-PCR) test was used to test Patients for COVID-19. Epi-data version 3.2 was used for data entry, and the final data analysis was through STATA version 14. After checking the assumption P-value<0.25 in the bivariable analysis was used to select a candidate variable for multi-variable analysis, and a p-value of <0.05 was used to declare statistical significance.<h4>Results</h4>In this study, the prevalence of ARDS was 32%. Almost all the patients had the clinical feature of cough (93.7%), followed by shortness of breath (79.9%), fever (77.7%), and headache (67%). Age older than 65 years (AOR = 3.35, 95%CI = 1.31, 8.55), male gender (AOR = 5.63, 95%CI = 2.15, 14.77), and low oxygen saturation level (AOR = 4.60, 95%CI = 1.15, 18.35) were the independent predictors of ARDS among severe COVID-19 patients.<h4>Conclusion</h4>The prevalence of ARDS among patients with severe COVID-19 was high in the study area. Therefore, elders and patients with critical conditions (low oxygen saturation) better to get special attention during COVID-19 case management to enhance good care and monitoring of the patients.https://doi.org/10.1371/journal.pone.0267835 |
| spellingShingle | Tadesse Tolossa Emiru Merdassa Atomssa Getahun Fetensa Lami Bayisa Diriba Ayala Ebisa Turi Bizuneh Wakuma Diriba Mulisa Dejene Seyoum Ayantu Getahun Tesfaye Shibiru Ginenus Fekadu Markos Desalegn Haile Bikila Acute respiratory distress syndrome among patients with severe COVID-19 admitted to treatment center of Wollega University Referral Hospital, Western Ethiopia. PLoS ONE |
| title | Acute respiratory distress syndrome among patients with severe COVID-19 admitted to treatment center of Wollega University Referral Hospital, Western Ethiopia. |
| title_full | Acute respiratory distress syndrome among patients with severe COVID-19 admitted to treatment center of Wollega University Referral Hospital, Western Ethiopia. |
| title_fullStr | Acute respiratory distress syndrome among patients with severe COVID-19 admitted to treatment center of Wollega University Referral Hospital, Western Ethiopia. |
| title_full_unstemmed | Acute respiratory distress syndrome among patients with severe COVID-19 admitted to treatment center of Wollega University Referral Hospital, Western Ethiopia. |
| title_short | Acute respiratory distress syndrome among patients with severe COVID-19 admitted to treatment center of Wollega University Referral Hospital, Western Ethiopia. |
| title_sort | acute respiratory distress syndrome among patients with severe covid 19 admitted to treatment center of wollega university referral hospital western ethiopia |
| url | https://doi.org/10.1371/journal.pone.0267835 |
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