Fatal pulmonary embolism in hospitalized patients. Clinical diagnosis versus pathological confirmation

OBJECTIVE - To assess the incidence of fatal pulmonary embolism (FPE), the accuracy of clinical diagnosis, and the profile of patients who suffered an FPE in a tertiary University Hospital. METHODS - Analysis of the records of 3,890 autopsies performed at the Department of General Pathology from Jan...

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Main Authors: Cláudio Tinoco Mesquita, José Laerte Boechat Morandi Júnior, Flávia Teixeira Perrone, Cláudia da Silva Oliveira, Lavínia J. Barreira, Sônia Santos C. A Nascimento, Raul Carlos Pareto Júnior, Evandro Tinoco Mesquita
Format: Article
Language:English
Published: Sociedade Brasileira de Cardiologia (SBC) 1999-09-01
Series:Arquivos Brasileiros de Cardiologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X1999000900001
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author Cláudio Tinoco Mesquita
José Laerte Boechat Morandi Júnior
Flávia Teixeira Perrone
Cláudia da Silva Oliveira
Lavínia J. Barreira
Sônia Santos C. A Nascimento
Raul Carlos Pareto Júnior
Evandro Tinoco Mesquita
author_facet Cláudio Tinoco Mesquita
José Laerte Boechat Morandi Júnior
Flávia Teixeira Perrone
Cláudia da Silva Oliveira
Lavínia J. Barreira
Sônia Santos C. A Nascimento
Raul Carlos Pareto Júnior
Evandro Tinoco Mesquita
author_sort Cláudio Tinoco Mesquita
collection DOAJ
description OBJECTIVE - To assess the incidence of fatal pulmonary embolism (FPE), the accuracy of clinical diagnosis, and the profile of patients who suffered an FPE in a tertiary University Hospital. METHODS - Analysis of the records of 3,890 autopsies performed at the Department of General Pathology from January 1980 to December 1990. RESULTS - Among the 3,980 autopsies, 109 were cases of clinically suspected FPE; of these, 28 cases of FPE were confirmed. FPE accounted for 114 deaths, with clinical suspicion in 28 cases. The incidence of FPE was 2.86%. No difference in sex distribution was noted. Patients in the 6th decade of life were most affected. The following conditions were more commonly related to FPE: neoplasias (20%) and heart failure (18.5%). The conditions most commonly misdiagnosed as FPE were pulmonary edema (16%), pneumonia (15%) and myocardial infarction (10%). The clinical diagnosis of FPE showed a sensitivity of 25.6%, a specificity of 97.9%, and an accuracy of 95.6%. CONCLUSION - The diagnosis of pulmonary embolism made on clinical grounds still has considerable limitations.
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spelling doaj.art-20ef23a1ada24c90bcfe1cbb62e747bf2022-12-21T17:48:47ZengSociedade Brasileira de Cardiologia (SBC)Arquivos Brasileiros de Cardiologia0066-782X1678-41701999-09-0173325525810.1590/S0066-782X1999000900001Fatal pulmonary embolism in hospitalized patients. Clinical diagnosis versus pathological confirmationCláudio Tinoco MesquitaJosé Laerte Boechat Morandi JúniorFlávia Teixeira PerroneCláudia da Silva OliveiraLavínia J. BarreiraSônia Santos C. A NascimentoRaul Carlos Pareto JúniorEvandro Tinoco MesquitaOBJECTIVE - To assess the incidence of fatal pulmonary embolism (FPE), the accuracy of clinical diagnosis, and the profile of patients who suffered an FPE in a tertiary University Hospital. METHODS - Analysis of the records of 3,890 autopsies performed at the Department of General Pathology from January 1980 to December 1990. RESULTS - Among the 3,980 autopsies, 109 were cases of clinically suspected FPE; of these, 28 cases of FPE were confirmed. FPE accounted for 114 deaths, with clinical suspicion in 28 cases. The incidence of FPE was 2.86%. No difference in sex distribution was noted. Patients in the 6th decade of life were most affected. The following conditions were more commonly related to FPE: neoplasias (20%) and heart failure (18.5%). The conditions most commonly misdiagnosed as FPE were pulmonary edema (16%), pneumonia (15%) and myocardial infarction (10%). The clinical diagnosis of FPE showed a sensitivity of 25.6%, a specificity of 97.9%, and an accuracy of 95.6%. CONCLUSION - The diagnosis of pulmonary embolism made on clinical grounds still has considerable limitations.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X1999000900001pulmonary embolismmortalityclinical diagnosis
spellingShingle Cláudio Tinoco Mesquita
José Laerte Boechat Morandi Júnior
Flávia Teixeira Perrone
Cláudia da Silva Oliveira
Lavínia J. Barreira
Sônia Santos C. A Nascimento
Raul Carlos Pareto Júnior
Evandro Tinoco Mesquita
Fatal pulmonary embolism in hospitalized patients. Clinical diagnosis versus pathological confirmation
Arquivos Brasileiros de Cardiologia
pulmonary embolism
mortality
clinical diagnosis
title Fatal pulmonary embolism in hospitalized patients. Clinical diagnosis versus pathological confirmation
title_full Fatal pulmonary embolism in hospitalized patients. Clinical diagnosis versus pathological confirmation
title_fullStr Fatal pulmonary embolism in hospitalized patients. Clinical diagnosis versus pathological confirmation
title_full_unstemmed Fatal pulmonary embolism in hospitalized patients. Clinical diagnosis versus pathological confirmation
title_short Fatal pulmonary embolism in hospitalized patients. Clinical diagnosis versus pathological confirmation
title_sort fatal pulmonary embolism in hospitalized patients clinical diagnosis versus pathological confirmation
topic pulmonary embolism
mortality
clinical diagnosis
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X1999000900001
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