Structure, mechanical characteristics, biodegradation, and in vitro cytotoxicity of magnesium alloy ZX11 processed by rotary swaging
Rotary swaging (RS) of alloy Mg–1.03Zn–0.66Ca (ZX11) was shown to refine the average grain size to 4.5 ± 1.2 µm in a longitudinal section and 4.8 ± 0.9 µm in a transverse section. In addition, a small amount of Mg2Ca particles about 300 nm in size and Mg6Zn3Ca2 particles with a size of about 100 nm...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2020-12-01
|
| Series: | Journal of Magnesium and Alloys |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221395672030147X |
| _version_ | 1797203761626611712 |
|---|---|
| author | Natalia Martynenko Natalia Anisimova Mikhail Kiselevskiy Natalia Tabachkova Diana Temralieva Dmitry Prosvirnin Vladimir Terentiev Andrey Koltygin Vladimir Belov Mikhail Morosov Vladimir Yusupov Sergey Dobatkin Yuri Estrin |
| author_facet | Natalia Martynenko Natalia Anisimova Mikhail Kiselevskiy Natalia Tabachkova Diana Temralieva Dmitry Prosvirnin Vladimir Terentiev Andrey Koltygin Vladimir Belov Mikhail Morosov Vladimir Yusupov Sergey Dobatkin Yuri Estrin |
| author_sort | Natalia Martynenko |
| collection | DOAJ |
| description | Rotary swaging (RS) of alloy Mg–1.03Zn–0.66Ca (ZX11) was shown to refine the average grain size to 4.5 ± 1.2 µm in a longitudinal section and 4.8 ± 0.9 µm in a transverse section. In addition, a small amount of Mg2Ca particles about 300 nm in size and Mg6Zn3Ca2 particles with a size of about 100 nm was detected. This resulted in pronounced strengthening: the yield strength and the ultimate tensile strength rose to 210 ± 8 MPa and 276 ± 6 MPa, respectively, while the elongation hardly decreased (22.0 ± 1.8% and 18.3 ± 2.9% before and after RS). Furthermore, RS led to an increase in the fatigue limit of the alloy from 120 MPa to 135 MPa and did not impair its resistance to chemical corrosion. The studies in vitro showed that ZX11 induces hemolysis without inhibiting the viability of peripheral blood mononuclear cells and has a more pronounced cytotoxic effect on tumor cells in comparison with non-transformed cells. No significant difference of the latter effect between the initial and the deformed states was observed. |
| first_indexed | 2024-04-24T08:24:28Z |
| format | Article |
| id | doaj.art-20f0421220604b939c31d56b53deee8e |
| institution | Directory Open Access Journal |
| issn | 2213-9567 |
| language | English |
| last_indexed | 2024-04-24T08:24:28Z |
| publishDate | 2020-12-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Journal of Magnesium and Alloys |
| spelling | doaj.art-20f0421220604b939c31d56b53deee8e2024-04-16T23:23:21ZengKeAi Communications Co., Ltd.Journal of Magnesium and Alloys2213-95672020-12-018410381046Structure, mechanical characteristics, biodegradation, and in vitro cytotoxicity of magnesium alloy ZX11 processed by rotary swagingNatalia Martynenko0Natalia Anisimova1Mikhail Kiselevskiy2Natalia Tabachkova3Diana Temralieva4Dmitry Prosvirnin5Vladimir Terentiev6Andrey Koltygin7Vladimir Belov8Mikhail Morosov9Vladimir Yusupov10Sergey Dobatkin11Yuri Estrin12National University of Science and Technology ''MISIS'', Leninsky prospect, 4, 119049 Moscow, Russia; A.A. Baikov Institute of Metallurgy and Materials Science of the RAS, Leninsky prospect, 49, 119334 Moscow, Russia; Corresponding author at: National University of Science and Technology ''MISIS'', 119049 Moscow, Leninsky prospect, 4, Russia.National University of Science and Technology ''MISIS'', Leninsky prospect, 4, 119049 Moscow, Russia; «N.N. Blokhin National Medical Research Center of Oncology» of the Ministry of Health of the Russian Federation, Kashirskoye Highway, 23, 115478 Moscow, RussiaNational University of Science and Technology ''MISIS'', Leninsky prospect, 4, 119049 Moscow, Russia; «N.N. Blokhin National Medical Research Center of Oncology» of the Ministry of Health of the Russian Federation, Kashirskoye Highway, 23, 115478 Moscow, RussiaNational University of Science and Technology ''MISIS'', Leninsky prospect, 4, 119049 Moscow, Russia; A.M. Prokhorov General Physics Institute of the RAS, Vavilova st., 38, Moscow 119991, RussiaNational University of Science and Technology ''MISIS'', Leninsky prospect, 4, 119049 Moscow, Russia; A.A. Baikov Institute of Metallurgy and Materials Science of the RAS, Leninsky prospect, 49, 119334 Moscow, RussiaA.A. Baikov Institute of Metallurgy and Materials Science of the RAS, Leninsky prospect, 49, 119334 Moscow, RussiaA.A. Baikov Institute of Metallurgy and Materials Science of the RAS, Leninsky prospect, 49, 119334 Moscow, RussiaNational University of Science and Technology ''MISIS'', Leninsky prospect, 4, 119049 Moscow, RussiaNational University of Science and Technology ''MISIS'', Leninsky prospect, 4, 119049 Moscow, RussiaA.A. Baikov Institute of Metallurgy and Materials Science of the RAS, Leninsky prospect, 49, 119334 Moscow, RussiaA.A. Baikov Institute of Metallurgy and Materials Science of the RAS, Leninsky prospect, 49, 119334 Moscow, RussiaNational University of Science and Technology ''MISIS'', Leninsky prospect, 4, 119049 Moscow, Russia; A.A. Baikov Institute of Metallurgy and Materials Science of the RAS, Leninsky prospect, 49, 119334 Moscow, RussiaDepartment of Materials Science and Engineering, Monash University, Clayton, Melbourne VIC 3800, Australia; Department of Mechanical Engineering, The University of Western Australia, Crawley, Perth WA 6009, AustraliaRotary swaging (RS) of alloy Mg–1.03Zn–0.66Ca (ZX11) was shown to refine the average grain size to 4.5 ± 1.2 µm in a longitudinal section and 4.8 ± 0.9 µm in a transverse section. In addition, a small amount of Mg2Ca particles about 300 nm in size and Mg6Zn3Ca2 particles with a size of about 100 nm was detected. This resulted in pronounced strengthening: the yield strength and the ultimate tensile strength rose to 210 ± 8 MPa and 276 ± 6 MPa, respectively, while the elongation hardly decreased (22.0 ± 1.8% and 18.3 ± 2.9% before and after RS). Furthermore, RS led to an increase in the fatigue limit of the alloy from 120 MPa to 135 MPa and did not impair its resistance to chemical corrosion. The studies in vitro showed that ZX11 induces hemolysis without inhibiting the viability of peripheral blood mononuclear cells and has a more pronounced cytotoxic effect on tumor cells in comparison with non-transformed cells. No significant difference of the latter effect between the initial and the deformed states was observed.http://www.sciencedirect.com/science/article/pii/S221395672030147XMagnesium alloyRotary swagingMechanical characteristicsHemolysisCell viabilityCytotoxicity |
| spellingShingle | Natalia Martynenko Natalia Anisimova Mikhail Kiselevskiy Natalia Tabachkova Diana Temralieva Dmitry Prosvirnin Vladimir Terentiev Andrey Koltygin Vladimir Belov Mikhail Morosov Vladimir Yusupov Sergey Dobatkin Yuri Estrin Structure, mechanical characteristics, biodegradation, and in vitro cytotoxicity of magnesium alloy ZX11 processed by rotary swaging Journal of Magnesium and Alloys Magnesium alloy Rotary swaging Mechanical characteristics Hemolysis Cell viability Cytotoxicity |
| title | Structure, mechanical characteristics, biodegradation, and in vitro cytotoxicity of magnesium alloy ZX11 processed by rotary swaging |
| title_full | Structure, mechanical characteristics, biodegradation, and in vitro cytotoxicity of magnesium alloy ZX11 processed by rotary swaging |
| title_fullStr | Structure, mechanical characteristics, biodegradation, and in vitro cytotoxicity of magnesium alloy ZX11 processed by rotary swaging |
| title_full_unstemmed | Structure, mechanical characteristics, biodegradation, and in vitro cytotoxicity of magnesium alloy ZX11 processed by rotary swaging |
| title_short | Structure, mechanical characteristics, biodegradation, and in vitro cytotoxicity of magnesium alloy ZX11 processed by rotary swaging |
| title_sort | structure mechanical characteristics biodegradation and in vitro cytotoxicity of magnesium alloy zx11 processed by rotary swaging |
| topic | Magnesium alloy Rotary swaging Mechanical characteristics Hemolysis Cell viability Cytotoxicity |
| url | http://www.sciencedirect.com/science/article/pii/S221395672030147X |
| work_keys_str_mv | AT nataliamartynenko structuremechanicalcharacteristicsbiodegradationandinvitrocytotoxicityofmagnesiumalloyzx11processedbyrotaryswaging AT nataliaanisimova structuremechanicalcharacteristicsbiodegradationandinvitrocytotoxicityofmagnesiumalloyzx11processedbyrotaryswaging AT mikhailkiselevskiy structuremechanicalcharacteristicsbiodegradationandinvitrocytotoxicityofmagnesiumalloyzx11processedbyrotaryswaging AT nataliatabachkova structuremechanicalcharacteristicsbiodegradationandinvitrocytotoxicityofmagnesiumalloyzx11processedbyrotaryswaging AT dianatemralieva structuremechanicalcharacteristicsbiodegradationandinvitrocytotoxicityofmagnesiumalloyzx11processedbyrotaryswaging AT dmitryprosvirnin structuremechanicalcharacteristicsbiodegradationandinvitrocytotoxicityofmagnesiumalloyzx11processedbyrotaryswaging AT vladimirterentiev structuremechanicalcharacteristicsbiodegradationandinvitrocytotoxicityofmagnesiumalloyzx11processedbyrotaryswaging AT andreykoltygin structuremechanicalcharacteristicsbiodegradationandinvitrocytotoxicityofmagnesiumalloyzx11processedbyrotaryswaging AT vladimirbelov structuremechanicalcharacteristicsbiodegradationandinvitrocytotoxicityofmagnesiumalloyzx11processedbyrotaryswaging AT mikhailmorosov structuremechanicalcharacteristicsbiodegradationandinvitrocytotoxicityofmagnesiumalloyzx11processedbyrotaryswaging AT vladimiryusupov structuremechanicalcharacteristicsbiodegradationandinvitrocytotoxicityofmagnesiumalloyzx11processedbyrotaryswaging AT sergeydobatkin structuremechanicalcharacteristicsbiodegradationandinvitrocytotoxicityofmagnesiumalloyzx11processedbyrotaryswaging AT yuriestrin structuremechanicalcharacteristicsbiodegradationandinvitrocytotoxicityofmagnesiumalloyzx11processedbyrotaryswaging |